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OB/GYN Boards > Review #1 > Flashcards

Review #1 Flashcards

1
Q

Most common cause of non-immune fetal hydrops

A

Monosomy X

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2
Q

Ultrasound features of Turner Syndrome

A

Coarctation of the aorta, short long bones, cystic hygroma

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3
Q

Risk of pregnancy for someone with Turner Syndrome

A

Aortic dissection

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4
Q

Cancers associated with BRCA

A

Prostate (BRCA1), pancreatic, melanoma (BRCA2), endometrial, gastric, biliary, colorectal

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5
Q

Peutz-Jeghers gene

A

STK11

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6
Q

Peutz-Jeghers cancers

A

Colon and rectal, pancreatic, stomach, small intestine

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7
Q

Li-Fraumeni gene

A

TP53

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8
Q

Li-Fraumeni cancers

A

Sarcoma, brain, leukemia, adenocortical

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9
Q

Cowden gene

A

PTEN

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10
Q

Cowden cancers

A

Endometrial, thyroid

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11
Q

Hereditary nonpolyposis colorectal cancer genes

A

MLH1, MSH1, MSH6, PMS2

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12
Q

HNPCC cancers

A

Colon, endometrial, gastric

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13
Q

CHEK2 cancers

A

Colorectal, prostate, male breast, thyroid, kidney

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14
Q

PALB2 cancers

A

Pancreatic, prostate

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15
Q

ATM cancers

A

Leukemias and lymphomas

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16
Q

Oligohydramnios

A

AFI < 5 cm, MVP < 2 cm

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17
Q

Polyhydramnios

A

AFI > 24 cm, MVP > 8 cm

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18
Q

AFI that warrants amnioreduction

A

> 35 cm

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19
Q

Indication for antibiotics in HSG

A

Hydrosalpinx

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20
Q

Risk of heterotopic pregnancy in IVF

A

1/100

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21
Q

Angelman vs Prader-Willi genetics

A

Imprinting
Angelman - maternal
Prader-Willi - paternal

22
Q

Treatment for Group A strep

A

Penicillin G and clindamycin

23
Q

Antibiotics for fourth degree laceration?

A

No

24
Q

History indicated cerclage indication

A

One or more second trimester loss without labor or abruption

25
Q

History indicated cerclage timing

A

12-14 wga

26
Q

Ultrasound indicated cerclage indications

A

Singleton, history of preterm birth, CL <25 mm

27
Q

Ultrasound indicated cerclage timing

A

16-23 wga

28
Q

Physical exam indicated cerclage indications

A

Dilated cervix at 16-23 wga

29
Q

Primary syphilis symptoms

A

Painless chancre that develops about 21 days after infection and resolves 3-6 weeks later

30
Q

Secondary syphilis symptoms

A

2-10 weeks after chancre, adenopathy, constitutional symptoms, doffuse papular rash involving palms and soles, condyloma lata in moist folds

31
Q

Tertiary syphilis symptoms

A

Aortitis, neurosyphilis, gummas

32
Q

Early syphilis treatment

A

Penicillin G 2.4 million units IM once

33
Q

Late syphilis treatment

A

Penicillin G 2.4 million units IM weekly for 3 weeks

34
Q

Couvaire uterus

A

Caused by blood flow into myometrium during severe placental abruption

35
Q

Tumor marker associated with granulosa cell tumor

A

Inhibin

36
Q

Muscles potentially torn in second degree laceration

A

Pubococcygeus, bulbocavernosus, transverse perineal

37
Q

Chromosomes of BRCA 1, 2

A

17 and 13

38
Q

Stage egg is frozen for social cryopreservation

A

Mature oocyte: haploid cell with one polar body

39
Q

Treatment for prolactinoma

A

Dopamine agonist: cabergoline (less side effects) or bromocriptine

40
Q

Single agent chemo for nonmetastatic GTN

A

Methotrexate or actinomycin D

41
Q

Contraindication to Elagolix

A

Pregnancy, elevated LFTs

42
Q

Isolated ultrasound finding that confers greatest risk for trisomy 21

A

Thickened NT

43
Q

What type of gene is HER2?

A

Oncogene, encodes erbB2 tyrosine kinase, a constituively active protein that amplifies cell replication

44
Q

Mechanism of trastuzumab

A

Monoclonal antibody to inactivate HER2/neu receptor tyrosine kinase

45
Q

Inheritance pattern of BRCA

A

Autosomal dominant

46
Q

HPV, type of virus

A

Double stranded DNA

47
Q

Adverse effect of trastizumab

A

Cardiotoxicity

48
Q

Drug used in postmenopausal women with ER/PR+ breast cancer

A

Anastrozole

49
Q

Anastrozole mechanism

A

Aromatase inhibitor that prevents conversion of androgens to estrogen

50
Q

SERM used in prevention of postmenopausal osteoporosis

A

Raloxifene

OB/GYN Boards (8 decks)

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