rev Flashcards
pharmacological management of acromegaly
somatostation analogue = ocreotide
causes of secondary hypothyroidism
hypopituitarism
- adenoma
- ablative therapy
- pituitary trauma
young female, unwell, weight loss, amenorrhea, hyperkalaemic, hyponatraemic, golden skin
addisons
hypercalcaemia treatment
fluids + bisphophonates
why is the macula red (cherry red spot) in patients with central retinal artery occlusion?
macula is thin + choroidal blood supply can be seen through the cells of the macula
aid worker has returned from africa and notices that their eyelashes have inturned, why has this happened?
chlamydia (trachomatis) induced scaring
MoA of latanoprost
opens uveascleral outflow
sick day rules for T1DM
Never stop insulin: you may have to adjust the dose
Stay hydrated, (you can also drink any
other sugar free drink) every hour.
• Do not fast: maintain carbohydrate intake
• If you are unable to eat or drink or are vomiting, replace meals with
sugary fluids or ice cream
symptoms of high blood glucose
thirst
passing more urine than usual
tiredness
medication sick day rules for T2DM
STOP -
metformin - increase lactic acidosis risk
sufonylureas (gliclazide) - hypo, if you are eating normally continue them tho
GLP-1 analogues (exenatide) SLGT2 inhibitors (dapagliflozin)
once recovered from illnesses, how should T2 diabetics restart their medication?
take them as normal
diabetes causing GI autonomic neuropathy presentation?
gastroparesis - bloating, vomiting, eratic blood gluce control
–> mx = metoclopramide
chronic diarrhoea (at night) reflux
how is diabetic neuropathic pain managed?
same way as other forms of neuropathic pain
–> amitriptyline -> duloxetine -> gabapentin -> pregabalin
which cardiac abnormality is assoc with acromegaly?
cardiomyopathy
hypertension
arrhythmias
left ventricular hypertrophy
what might thyrotoxicosis with tender goitre indicate?
subacute (de quervains) thyroiditis
hyperthyroid state then hypothyroiid
