Restrictive Lung Disease

Question 1

in obstructive lung disease the problem is with

Answer 1

• exhaling

Question 2

in restrictive lung disease the problem is with

due to

Answer 2

• inhaling
• noncompliant lungs, chest wall
• weak inspiratory muscles

Question 3

hallmark of obesity

Answer 3

• reduced FRC which results in a lower RV

Question 4

if you see more blue in a slide of lung disease, that tells you the disease is more

what about pink

Answer 4

• cellular

- more fibrotic

Question 5

alveolar pattern looks more like

Answer 5

• cotton-wool appearing

Question 6

compliance of fibrotic lung

why

Answer 6

• low

- deposition of collagen makes the lung stiffer and harder to inflate

Question 7

a common disease that can mimic ILD is

Answer 7

• congestive heart failure

Question 8

chest X ray sign of congestive heart failure

Answer 8

• Kerley lines

Question 9

dense infiltrates with air bronchograms usually represent

Answer 9

• bacterial pneumonia

Question 10

two non-infectious ILDs that classically show peripheral consolidation with air bronchograms are

Answer 10

• cryptogenic organizing pneumonia

- eosinophilic pneumonia

Question 11

between NSIP and IPF, which is responsive to immunosuppressive therapy?

Answer 11

• NSIP (non-specific interstitial pneumonia)

Question 12

MOA of good pasture disease

target antigen

Answer 12

• anti-glomerular basement membrane antibody mediated disease
• type 4 collagen

Question 13

sarcoidosis is mediated by

Answer 13

• autoimmune

Question 14

sarcoidosis granulomas versus tuberculosis granulomas

Answer 14

• sarcoidosis is non-caseating

Question 15

cytokine profile in sarcoidosis

Answer 15

• Th1 polarized