Restricted Lung Disease Drugs

Question 1

Drugs used to Tx ARDS?

Answer 1

1. Albuterol (IV)
2. Inhaled NO
3. Inhaled Prostacyclin (PGI2)
   ^ Vasodilators
4. Corticosteriods
5. Dietary oil supplementation
   ^Anti-inflammatory

Question 2

Drugs used to Tx Neonatal-RDS

Answer 2

1. Antenatal corticosteriods - to all women at risk of delivery

Question 3

Drugs used to tx Sarcoidosis

Answer 3

1. Glucocorticoids or

2. Methotrexate (off label)

Question 4

Drugs used to tx Idiopathic Pulm fibrosis

Answer 4

1. Pirenidone

2. Nintedanib (TKI)

Question 5

Tx of Goodpasture’s Syndrome?

Answer 5

Plasmapheresis

Question 6

Labeled Tx of Wegner’s Granulomatosis

Answer 6

1. Rituximab

Question 7

Off label Tx of Wegner’s Granulomatosis

Answer 7

1. Azathioprine
2. Cyclophosphamide
3. Corticosteriods

Question 8

Tx of Pulmonary Arterial Hypertensin (PAH)

Answer 8

1. Prostanoids (all IV)
   - Epoprostenol
   - Iloprost
   - Treprostinil
2. Endothelin-1 Receptor antagonists (oral but teratogenic
   - Bosentan
   - Ambrisentan
3. PDE-5 inhibitors
   - sildenafil
   - Tadalafil
4. CCBs - Diltiazem, Nifedipine, Amlodipine

Question 9

Drugs used to Tx CF?

Answer 9

1. Ivacaftor

2. Lumacaftor/Ivacaftor