Bacterial Pneumonia Rx

Question 1

Organisms most likely to cause (CAP) pneumonia in those 0-6 weeks old?

Answer 1

1. Group B streptococci

2. E. coli

Question 2

Organisms most likely to cause (CAP) pneumonia in those 6 weeks to 18 yrs old?

Answer 2

1. Viruses
2. Mycoplasma Pneumoniae
3. Chlamydia pneumoniae
4. Streptococci pneumoniae

Question 3

Organisms most likely to cause (CAP) pneumonia in those 18 to 40 yrs old?

Answer 3

1. Mycoplasma Pneumoniae

2. Streptococci pneumoniae

Question 4

Organisms most likely to cause (CAP) pneumonia in those 40 to 65 yrs old?

Answer 4

1. Streptococci pneumoniae
2. Haemophilus Infleunzae
3. Anerobes (GP or GN)
4. Viruses
5. Mycoplasma Pneumoniae

Question 5

Organisms most likely to cause (CAP) pneumonia in those 65+ years old?

Answer 5

1. Streptococci pneumoniae
2. Viruses
3. Anerobes
4. Haemophilus Infleunzae
5. Gram Postive Rods

Question 6

Organisms most likely to cause nocosomial pneumonia?

Answer 6

1. S. aureus

2. P. Aeruginosa

Question 7

Organisms most likely to cause pneumonia in alcoholics?

Answer 7

1. Klebsiella pneumoniae

Question 8

Viruses most likely to cause pneumonia? In what age range does this occur?

Answer 8

1. Influenza
2. Adenoviruses
3. Rhinovirus
4. Respiratory syncytial virus (RSV)

• 6wks-18yrs old
• 40-65yrs
• 65+

Question 9

Epidemiology for Legionnarie’s Disease?

Answer 9

• Men > 50yrs old
• Smokers with Chronic Lung disease
• Immunocompromised

Question 10

Most common Rx for Legionnarie’s Disease?

Answer 10

Newer macrolides:

1. Azithromycin
2. Clarithromycin
   - CYP

• 3. Respiratory quinolones: Levofloxacin, Ciprofloxacin, moxifloxacin
• For severely ill: Rifampin used in combo with above Rx. But watch for CYP!

Question 11

Drugs indicated for Hospital Acquired Pneumonia (HAP)

Answer 11

1. Imipenem-Cilastin
2. Aztreonam
3. Ceftazidime
4. Vancomycin

Question 12

Drugs indicated for aspiration pneumonia

Answer 12

1. Clindamycin

or alternatively: Ampicillin-Sulbactam

Question 13

Drugs indicated for Acute bronchitis?

Answer 13

1. Amoxicillin+Clavulanic acid
2. Azithromycin
3. Clarithromycin
4. Doxycycline

• For severe or resistant cases:
  1. Ciprofloxacin

Question 14

Drugs indicated for lung abscesses

Answer 14

1. Clindamycin
2. Ceftriaxone + *Metronidazole
   (2 for nocosomial infections)

Question 15

Drugs indicated for CAP

Answer 15

1. Azithromycin
2. Levofloxin
3. Amoxicillin/clavulanate