Resting Membrane Potentials Flashcards
Describe the differences in ionic composition of intra- and extra- cellular fluids
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Describe the ionic basis of the resting membrane potential
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Explain what is meant by membrane depolarization or hyperpolarization and the roles of the major ion-specific channels in the plasma membrane
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outline how membrane potential is ‘set up’ and how it may be changed by mechanisms involved in cellular signalling
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Outline what a membrane potential is, how the resting potential of a cell may be measured and the range of values found
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Explain the concept of selective permeability, and how the selective permeability of cell membranes arises
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Describe how the resting potential is maintained given the distribution of ions across cell membranes
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Explain the term equilibrium potential for an ion and calculateits value from the ionic concentrations on either side of the plasma membrane
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Define depolarization and hyperpolarization, and explain the mechanisms that may lead to each of these
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Explain how changes in ion channel activity can lead to changes in membrane potential, and outline some of the roles of the membrane potential in signalling within and between cells
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Outline how ligand-gated channels can give rise to synaptic potentials
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