Action Potentials

Question 1

Describe the properties of the action potential, its ionic basis and the associated changes in membrane ionic permeability

Answer 1

a

Question 2

Describe the basis of the all-or-nothing law and refractoriness in terms of these changes in permeability

Answer 2

a

Question 3

Describe the key molecular properties of ion channels

Answer 3

a

Question 4

Outline the action of local anaesthetics

Answer 4

s

Question 5

Describe the results of extracellular recording and how this can be used to measure conduction velocity

Answer 5

a

Question 6

Explain how axons are raised to threshold

Answer 6

a

Question 7

Explain the local circuit theory of propagation

Answer 7

A

Question 8

Explain how conduction velocity is linked to fibre diameter

Answer 8

A

Question 9

Explain the implications of myelination for conduction

Answer 9

A

Question 10

Describe certain consequences of demyelination

Answer 10

a

Question 11

Explain how action potentials open Ca2+channels

Answer 11

a

Question 12

Describe some aspects of Ca2+ channel diversity and function

Answer 12

a

Question 13

Describe events underlying fast synaptic transmission

Answer 13

a

Question 14

Describe some properties of ligand gated ion channels

Answer 14

a

Question 15

Explain how neuromuscular blockers work

Answer 15

a

Question 16

Explain why myasthenia gravis causes weakness

Answer 16

a

Question 17

illustrate the change in membrane potential that occurs during an action potential

Answer 17

a

Question 18

describe how the ionic movements underlying the action potential occur

Answer 18

a

Question 19

outline the properties of voltage-activated ion channels

Answer 19

a

Question 20

explain the basis of refractoriness in nerve and muscle

Answer 20

a