Respiratory system TT Flashcards
Topic 1: Intro to resp system
What are 8 common disorders that affect the respiratory system?
- infections
- allergic rhinitis
- coughs
- colds
- congestion
- asthma
- COPD
- COVID-19 (SARS-CoV-2)
What are 8 drug categories that affect the respiratory system?
- antihistamines
- decongestants
- antitussives
- mucolytics
- expectorants
- bronchodilators
- leukotriene modifiers
- mast cell stabilisers
What are the 2 types of respiration?
- external: breathing
- internal: cellular
What does breathing do to O2 and CO2?
breathing brings in O2 from the atmosphere and transfers CO2 in the opposite direction
What are the 2 types of internal respiration?
where do they occur
- aerobic
- anaerobic
both energy-producing processes going on in cells
What is the respiration equation?
C6H12O6 + 6O2 —–> 6CO2 + 6H2O
ATP
energy required for life comes form what?
and what must happen to it to release energy stored inside it
comes form food.
must be OXIDISED, release energy
similarities between the cardiovascular and respiratory system?
(what type of flow do they use? what process allows the movement of gases?
- highly efficient convective bulk flow systems (ventilatory + circulatory) for long-distance transport of gases or liquid
- diffusion for short-distance movements: O2 & CO2
What is the metabolic rate also the rate of?
O2 consumption
What is V̇O2? What is the average value at rest?
O2 consumed per unit time
~250ml/min
What is V̇CO2? What is the average value at rest?
CO2 produced
200ml/min
What is RQ? What is the formula for it?
Respiratory quotient:
V̇O2/V̇CO2 = 200/250 = 0.8
When is the value of RQ 0.8?
when the person has a mixed diet of fats, carbohydrates and proteins
What is the RQ value for
- fats
- carbs
- proteins
- 0.7
- 1
- 0.8
How do V̇O2 and V̇CO2 change when exercising and why? How much is it?
BOTH: increase:
tissues consume more O2 so need more
tissues produce vast amounts of CO2
3000ml/min
Why is the respiratory system important with metabolic changes? (think V̇O2 and V̇CO2)
- if blood O2 falls due to increased O2 consumption and respiratory system doesn’t restore, tissues become hypoxic
- if blood CO2 rises and isn’t removed, pH would be disturbed
What is the consequence of blood O2 falling?
tissues become hypoxic
What is the consequence of blood CO2 rising?
pH disturbances
If the lungs regulate CO2 levels in the blood, what does that make it a regulator of?
an acid-base regulator
How does respiration change if V̇O2 doubles?
respiration also doubles - in direct proportion to the metabolic demand
What is the consequence of ventilation changing in direct proportion to metabolic demand?
the blood gases and pH are kept relatively constant
In a diseased state, can respiration meet metabolic demands? What are the consequences?
no, blood gases and pH are abnormal
In a less severe diseased state, when can respiration not meet the metabolic demand?
when the metabolic demand changes e.g. during exercise
blood gases and pH= abnormal
In a more severe diseased state, when can respiration not meet the metabolic demand?
at rest