Respiratory system - Gas Exchange Flashcards

1
Q

What is the trachea lined with?

A

Ciliated epithelium cells with goblet cells

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2
Q

What are the goblet cells for?

A

To produce mucus to trap cells

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3
Q

Describe the alveolar ducts

A

No cartilage or ciliated epitherlium

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4
Q

What is gas exchange?

A

Movement of respiratory gases in and out of the body tissues

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5
Q

What causes a larger concentration gradient at alveoli?

A

High concentration of O2 than in blood

Blood flow in capillary brings de-oxygenated blood low O2 but high in CO2

Ventilation brings air rich in O2 to remove CO2

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6
Q

What makes alveoli have a large surface area?

A

Millions alveoli

Rounded shape

More gas exchange at one time

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7
Q

What makes alveoli have a thin and permeable surface?

A

Layer moisture

Squamous endothelial cells

Short distance between alveoli and capillaries

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8
Q

What is ventilation?

A

Movements that cause air to flow in and out of the respiratory system

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9
Q

What kind of process is ventilation?

A

Active process

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10
Q

What happens to the diaphragm an E,I,M during inspiration?

A

Contract

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11
Q

What happens when the diaphragm contracts?

A

Flattens

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12
Q

What happens to the E.I.M when they contract?

A

Ribs move up and out

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13
Q

What happens to the volume of thorax during inspiration?

A

Increases

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14
Q

What happens to the pressure in the alveoli and thorax during inspiration?

A

Decreases

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15
Q

What happens to the diaphragm and E.I.M during expiration?

A

Relaxes

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16
Q

What happens to the diaphragm when it relaxes?

A

Domes

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17
Q

What happens to the E.I.M when it relaxes?

A

Ribs move in and down

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18
Q

What happens to the volume in the thorax during expiration?

A

Decreases

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19
Q

What happens to the pressure in the alveoli and thorax during expiration?

A

Increases

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20
Q

How does air move during expiration?

A

Forced out

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21
Q

What happens during strenous exercise with expiration?

A

Internal intercostal muscles are used to move ribs down rapidly

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22
Q

What is tidal volume?

A

The volume of air a human breaths in and out of their lungs at each breath when at rest

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23
Q

What is inspiratory reserve volume?

A

The maximum volume of air that can be taken in above tidal volume

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24
Q

What is expiratory reserve volume?

A

The maximum amount of air that can be breathed out above tidal volume

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25
What is residual volume?
The volume of air remaining in lungs after each breath
26
What is vital capacity?
The volume of air exchanged at a deep breath - sum of tidal volume, IRV and ERV
27
What is total lung volume?
Vital capacity + residual volume
28
What 2 ways can the respiratory system can be monitored?
Peak flow and spirometry
29
What is peak flow used to measure?
The force with which a person can exhale
30
What is the scale for the peak flow?
Litres of air per minute
31
How is the peak flow used?
Set scale to 0 Hold horizontally Sit up and take deep breath Seal lips Breath out fast and hard 3x repeat Highest value recorded
32
How does peak flow change with aging?
Decreases as elasticity in lungs decrease
33
How does peak flow change with height?
Increases
34
What is the average peak flow of a 35 yr old male?
625 l min-1
35
What is the average peak flow of a 35 yr old female?
430 l min-1
36
What is spirometry used to measure?
Tidal volume Breathing rate Inspiratory and expiratory reserves
37
How is the spirometre used?
Nose is sealed Sit up and deep breath Seal mouth on mouth piece Breath out Fast and Long Repeat 3x Average
38
What causes cystic fibrosis?
Recessive genetic mutation
39
What does this mutation is CF impact protein?
The protein called CFTR chnages so unable to transport chloride ions properly
40
Why is a CF sufferer tired?
Less aerobic respiration so less ATP produced so no energy
41
What is the difficulty with thick sticky mucus with regards to breathing?
It increases the diffusion distance so gas exchange is slower
42
Why is a CF sufferer breathless?
Less O2 enters the blood
43
What kind of condition is emphysema?
Progressive
44
What causes emphysema?
Exposure to tobacco smoke or toxic chemicals
45
How does emphysema impact the bronchioles?
Collapse them so air traps in alveoli
46
What happens to the alveoli when the bronchioles collapse?
Unable to recoil efficiently and cannot expel air fully so alveoli over-expand and rupture
47
What happens to the amount of alveoli in emphysema?
Fewer
48
How is air space in alveolous with emphysema?
Larger air space
49
How is surface area with emphysema?
Reduced so gas exchange is slower so less oxygenated blood
50
Symptoms of emphysema?
Shortness of breath Hyperventilation Expanded chest
51
What does COPD stand for?
Chronic Obstructive Pulmonary Disease
52
What are the two types of CODP?
Emphysema and Chronic Bronchitis
53
What causes chronic bronchitis?
Long term exposure to tobacco smoke and air pollution
54
What is inflammed with chronic bronchitis?
The lining of the bronchi
55
What encourage bacteria growth with chronic bronchitis?
Over-production of mucus which restricts movement
56
Why is there less O2 with chronic bronchitis?
Reduced diffusion gradient so less gas exchange
57
How does respiration change with exercise?
Increases
58
How does exercise impact pH?
Reduces it as more CO2
59
What detects change in pH in blood?
Chemoreceptors in aorta or carotid artery
60
Where do the detectors of change send impulses?
Medulla
61
Where does the medulla send impulses and to do what?
Respiratory centre to cause more contraction of diaphragm and intercostal muscles
62
What do more impulses cause in the respiratory system?
Increase depth of breathing to remove CO2