respiratory system and digestion Flashcards

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1
Q

partial pressure

A

fractional conc of specific gas relative to other gases present

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2
Q

what drives diffusion

A

difference in partial pressure

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3
Q

what drives respiration

A

O2

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4
Q

respiration byproduct

A

CO2

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5
Q

diffusion physically

A

maximize surface area and concentration gradient

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6
Q

pressure in lungs as you breath

A

neg pressure brings air into your lungs -> positive pressure as you breath out

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7
Q

what part of NS governs breathing

A

both somatic and autonomic

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8
Q

how much energy does breathing require

A

little energy; passive process

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9
Q

capillary beds

A

a network of small blood vessels that allow the exchange of gas, water, and nutrient located in metabolic organs

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10
Q

tidal ventilation

A

like a wave; always fluctuating; stale air still in lung when you breath out

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11
Q

inhale

A

ontracts, expand thoracic cavity; neg pressure

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12
Q

exhale

A

relax, reducing volume of thoracic cavity; positive pressure; passive

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13
Q

why is breathing only 25% effect

A

because stale air in lungs even after you exhale

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14
Q

intercostal muscles

A

mechanical aspect of breathing by helping expand and shrink the size of the chest cavity

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15
Q

diaphragm

A

muscle that separates the thoracic (chest) and abdominal cavities in mammals

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16
Q

trachea

A

central airway leading to lungs

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17
Q

lungs

A

expand and contract during respiration; pleural cavity (slime) to prevent contact with ribcage

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18
Q

bronchi

A

supply air from trachea to the lungs
* trachea -> 2 primary bronchi, -> secondary bronchi -> bronchioles

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19
Q

bronchiole

A

tiny, fine branches of the bronchi that deliver air to alveoli sacs

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20
Q

alveoli

A

transport fresh oxygen into the body and carbon dioxide out of the bod

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21
Q

pulmonary capillaries

A

small blood vessels that supply blood to the alveolar wall

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22
Q

red blood cell function

A

carry oxygen from lungs to rest of body

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23
Q

why are red blood cells special

A

-3/4 of all cells in body
-no organelles or cytoplasm
- donut shaped
- 270 hemoglobin proteins per cell

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24
Q

hemoglobin binding sites

A

2 beta and 2 alpha O2 binding sites

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25
Q

hemoglobin saturation

A

saturated if all 4 binding spots bonded to O2

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26
Q

cooperative binding

A

once 1 O2 bonded to hemoglobin binding site, other sites what oxygen even more; exponential rate

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27
Q

lowest and highest partial pressures of oxygen in the body

A

???

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28
Q

pH affect on O2 PP and hemoglobin saturation

A

lower pH = higher H+ conc (from increased activity/ respiration)
- less saturated red blood cells because more byproducts of repsiration present to bind rather than O2

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29
Q

maternal vs fetal hemoglobin saturation

A

fetal hemoglobin more saturated because mother has to readily give up O2 to give to fetus

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30
Q

myoglobin

A

only has 1 binding site for O2; binds more readily to O2 and does not want to let go.

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31
Q

artery

A

carry blood away from the heart

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32
Q

vein

A

carry blood to the heart

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33
Q

veins below the heart: form and function

A

one way valve to help veins return blood to the heart

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34
Q

veins or artery: volume of blood in circulation

A

lower volume in artery

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35
Q

veins or artery: blood pressure

A

higher blood pressure in arteries

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36
Q

veins or artery: return rate

A

(more smooth muscle) faster return rate in arteries

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37
Q

veins or artery: muscles

A

more muscles in artery

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38
Q

resistance to blood flow (R) =

A

1/ (radius)^4

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39
Q

factors that impact resistance to blood flow

A

1) radius
2) distance traveled from heart, length of venule

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40
Q

rate of flow =

A

pressure/ resistance
*pressure (heart beat per min) required to overcome resistance

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41
Q

size of cross section vs. amount of circulatory system they makeup: aorta

A

largest cross section but make up least of system

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42
Q

size of cross section vs. amount of circulatory system they makeup: capillary beds

A

smallest cross section BUT make up most of system; maximize surface area for diffusion

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43
Q

distance from heart and velocity

A

further from heart = slowest velocity
* capillary beds = slowest

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44
Q

blood pressure vs osmotic pressure: arterial side

A

net force out of capillaries; blood pressure > osmotic pressure

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45
Q

blood pressure vs osmotic pressure:venous side

A

net force into capillaries; osmotic pressure > blood pressure

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46
Q

what goes into the capillary beds (venous side)

A

byproducts of respiration; CO2 and H+

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47
Q

3 chambered heart vs 4 chambered heart

A

4 chambered heart has separate chambers for O2 and CO2; maximizes gradient and is much more efficient

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48
Q

cardiac cycle: diastole

A

atria contracts -> fills ventricles (chambers) with blood; heart relaxes

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49
Q

cardiac cycle: systrole

A

ventricles contract -> pump blood out of the heart

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50
Q

heart depolarization process

A

1) SA node (pacemaker) node activated and atria contracts
2)AV node activated
3) action potentials sent through modified muscle (purkinje) fibers -> ventricles -> ventricles contract

51
Q

EKG

A

measure electrical impulses to look at heartbeat;
-small increase: atria contract
- large spike: ventricles contract

52
Q

atria

A

The two upper chambers in the heart , which receive blood from the veins and push it into the ventricles

53
Q

how sympathetic NS regulates heart

A

increases heartbeat;
norepinephrine excites SA, AV and muscles fibers -> increase unloading in cap. beds increased heartbeat

54
Q

how parasympathetic NS regulates heart

A

decrease heart rate to conserve energy via acetylcholine

55
Q

regulating high blood pressure

A

blood vessels relax

56
Q

regulating low blood pressure

A

blood vessels constrict
*ADH

57
Q

what muscles increase blood flow when we are active

A

skeletal muscles!!!

58
Q

3 parts of the gut

A

foregut, midgut, hindgut

59
Q

foregut

A

mouth- stomach; pre absorption

60
Q

midgut

A

small intestine; absorption

61
Q

hindgut

A

large intestine- anus; expelling waste

62
Q

inferior vena cava

A

drain deoxy blood from below the heart back to the heart

63
Q

superior vena cava

A

drain deoxy blood from above the heart back to the heart

64
Q

heart pumping blood to circuits

A

deoxygenated. blood -> heart -> pulmonary circuit (lungs) -> oxygenated blood to heart -> systemic circuit (body)

65
Q

how does blood get from heart to pulmonary circuit

A

blood -> right atrium -> right AV valve -> right ventricle -> pulmonary valve -> right and left pulmonary artery -> out

66
Q

where does blood enter the heart

A

right atrium

67
Q

how does blood get from heart to systemic circuit

A

right and left pulmonary veins (oxy blood) -> left atrium -> left AV valve -> left ventricle -> aorta

68
Q

capillaries vs alveoli

A

capillaries: are blood vessels in the walls of the alveoli; blood CO2/O2 exchange
alveoli: small air sacs where the exchange of oxygen and carbon dioxide takes place

69
Q

2 types of digestion

A

chemical and mechanical

70
Q

key component of chemical digestion

A

enzymes and acidic environments

71
Q

key components of mechanical digestion

A

teeth (grind/chew) and intestinal muscles (chern)

72
Q

mouth function

A

ingestion; teeth grind up food, saliva salivates (enzymes), tongue moves food around to help swallow

73
Q

enzymes in saliva

A

salivary amylase = breaks down carbs
salivary lipase = breaks down lipids

74
Q

what governs the movement of food through the digestive system

A

autonomic ns

75
Q

peristalsis

A

rhythmic muscular contraction that move food

76
Q

pyloric sphincter

A

band of muscles at the base of stomach that regulate how much food is released to small intestine

77
Q

stomach environment and its consequences

A

very acidic; proteins denature
* cells lining stomach secrete HCl to maintain pH

78
Q

gastin fluid

A

secreasted when food arrives in stomach -> stimulates HCl and pepsinogen production

79
Q

digestive enzymes in stomach

A

peptin (protein break down) and lipase (lipid break down)

80
Q

functions of stomach

A

digest and store food

81
Q

gastric glands

A

produce mucus to protect the stomach lining from HCl stomach acid

82
Q

chief cells

A

secrete pepsinogen

83
Q

parietal cells

A

secrete H+ and Cl- from cell separately -> HCl -> turn pepsinogen into pepsin

84
Q

pepsin

A

a stomach enzyme that serves to digest proteins found in ingested food

85
Q

small intestine function

A

absorb and digestion

86
Q

small intestine 3 parts

A

duodenum, jejunuim, ikeum

87
Q

duodenum function

A

receives food from stomach; has to neutralize pH

88
Q

how does duodenum neutralize pH

A

chemoreceptors bind to H+ from acidic stomach contents -> bind to hormone secretion -> signal release of bicarbonate

89
Q

how are fats digested

A

CCK hormone released -> signal gallbladder to release bile salts to digest fat

90
Q

where are bile salts made and stored

A

made in liver and stored in gallbladder

91
Q

common bile duct

A

transfer bile salt made in liver -> gallbladder

92
Q

pancreas function

A

creates enzymes for digestion
- endocrine: alpha cells for glucagon and beta cells for insulin
- exocrine: amylase, lipase, digest proteins

93
Q

absorption of glucose (sigars and amino acids)

A

glucose Na+ cotransporter; use conc gradient of Na+ to being glucose into cell with no ATP
* leaky glucose channels bring glucose to body

94
Q

what part of the small intestine absorbs

A

ileum

95
Q

hepatic portal system

A

drains spleen, pancreas, GI tract, gallbladder to liver

96
Q

liver functions

A

detoxify anything harmful, stores sugar as glycogen, gluconeogenesis (proteins and lipid -> sugar)

97
Q

large intestine

A

absorbing water and electrolytes, producing and absorbing vitamins, and forming and propelling feces toward the rectum for elimination

98
Q

large intestine gut microbiome

A

energy from byproducts of bacteria -> absorb

99
Q

gut microbiome; lactose intolerance

A

lactose not broken down -> large intestine where bacteria break it down and produce gas.

100
Q

osmoregulation systems: low water

A

hypothalamus creates feeling of thirst and signals posterior pituitary gland to release ADH -> kidney reabsorb more water

101
Q

osmoregulation systems: high water

A

hypothalamus signals for less release of ADH -> kidneys reabsorb less water and release through urine.

102
Q

how do you get water

A

food, water, byproduct of respiration

103
Q

how do we lose water

A

sweat and urine

104
Q

kidney function

A

get rid of nitrogenous compounds and save electrolytes and water by filtering blood

105
Q

3 steps kidney function

A

1) filtration (turn into filtrate)
2) reabsorption (usafal solvents back into blood)
3) secretion: adds solute to filtrate -> turns to urine when transported to bladder

106
Q

peritubular capillaries function

A

filter blood

107
Q

vasa recta funtion

A

reabsorption

108
Q

nephron

A

Each nephron has a glomerulus to filter your blood and a tubule that returns needed substances to your blood and pulls out additional wastes

109
Q

renal cortex

A

outer layer of the kidney

110
Q

renal medulla

A

inner part of the kidney; helps regulate the concentration of urine by filtering out water, salts, and acid

111
Q

glomerulus

A

filters blood

112
Q

Bowman’s capsule

A

forms extracellular space through filtration gradient

113
Q

distal convoluted tubule

A

regulates extracellular fluid volume and electrolyte homeostasis; connects to collecting duct

114
Q

proximal convoluted tubule

A

segment of the renal tubule responsible for the reabsorption and secretion of various solutes and water; closest to bowman’s capsule

115
Q

path to collecting duct

A

proximal convoluted tubule -> loop of henle -> distal convoluted tubule -> collecting duct.

116
Q

loop of henle

A

reabsorbs water

117
Q

descending limb

A

has aquaporins; increased osmolarity as water flows out through aquaporins

118
Q

ascending limb

A

has salt pumps; decreased osmolarity by actively pumping salt

119
Q

urea recycling

A

urea goes back into ascending limb so it pulls out more salt and water; upregulated ADH -> urea transport proteins and aquaporins

119
Q

high ADH effect on urine

A

increased permeability of collecting ducts -> water diffuse out of filtrate -> more conc urine

120
Q

low ADH effect urine

A

less permeable collecting duct -> less water diffusion -> more dilute urine

121
Q

how different organisms convert NH2

A

aquatic: NH3 (lots of water but low energy)
mammals: urea (less toxic but more energy)
birds, insects, reptiles: Uric acid (no water, energetically costly)

122
Q

endothelial tissue

A

type of tissue lines our capillaries and allows for the exchange of O2, CO2, nutrients, and effector cells of the immune system