Respiratory System Flashcards

1
Q

True or False: Type I pneumocytes are responsible for alveolar regeneration.

A

False, Type II pneumocytes handle regeneration and surfactant production.

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2
Q

What are the main functions of the respiratory system?

A

Smell, O2 and CO2 exchange, phonation.

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3
Q

Which immune cells are commonly found in the lamina propria?

A

Lymphocytes, eosinophils, macrophages, mast cells.

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4
Q

How does the epiglottis function in respiration?

A

It prevents food from entering the airway during swallowing.

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5
Q

How does smooth muscle contribute to bronchiole function?

A

It regulates airway diameter through contraction and relaxation.

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6
Q

Which part of the respiratory system has the highest resistance to airflow?

A

Bronchioles, due to their small diameter and smooth muscle regulation.

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7
Q

What are the functions of the paranasal sinuses?

A

Lighten the skull, warm and humidify air, contribute to voice resonance.

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8
Q

List the tissue layers of the trachea from innermost to outermost.

A

Mucosa, submucosa, cartilaginous layer, adventitia.

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9
Q

Explain the significance of the alveolar-capillary barrier.

A

It allows efficient gas exchange while preventing fluid leakage into the alveoli.

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10
Q

What structural adaptations help in air filtration in the nasal cavity?

A

Vibrissae (hair follicles) and sebaceous glands.

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11
Q

Fill in the blank: The trachea divides into the ______ at the carina.

A

Primary bronchi.

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12
Q

Why are the right and left primary bronchi different in size and orientation?

A

The right bronchus is wider and more vertical, making it more susceptible to foreign object aspiration.

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13
Q

What condition results from a deficiency of surfactant in newborns?

A

Neonatal respiratory distress syndrome (NRDS).

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14
Q

Explain the difference between the conducting and respiratory portions of the respiratory system.

A

The conducting portion conditions air (warming, moistening, filtering), while the respiratory portion facilitates gas exchange.

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15
Q

Explain the function of neuroendocrine cells in the respiratory system.

A

They regulate epithelial cell function.

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16
Q

List the structures that belong to the conducting portion of the respiratory system.

A

Nasal cavities, pharynx, larynx, trachea, bronchi, terminal bronchiole.

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17
Q

How do infections affect the respiratory mucosa?

A

They can cause inflammation, excessive mucus production, and damage to cilia.

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18
Q

What are Clara cells, and what is their function?

A

Non-ciliated cells in the bronchioles that secrete surfactant and help regenerate bronchial epithelium.

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19
Q

Describe the role of the trachealis muscle.

A

It adjusts the diameter of the trachea to regulate airflow.

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20
Q

How does metaplasia affect the tracheal epithelium?

A

It leads to loss or reduction of cilia, thickening of the basal membrane, and increased goblet cell numbers.

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21
Q

True or False: The bronchioles contain cartilage.

A

False, bronchioles lack cartilage.

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22
Q

Why is the left lung smaller than the right lung?

A

To accommodate the position of the heart.

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23
Q

Fill in the blank: The nasal cavity is lined with ______ epithelium in the respiratory region.

A

Pseudostratified ciliated columnar.

24
Q

What is the role of pulmonary surfactant in lung compliance?

A

It reduces surface tension, preventing alveolar collapse and making expansion easier.

25
What is the function of ciliated cells in the respiratory epithelium?
They move out particles and microorganisms.
26
What type of connective tissue is found in the submucosa of the trachea?
Loose connective tissue.
27
Fill in the blank: The trachea is approximately _______ cm long.
10-16 cm
28
What happens to the diaphragm during expiration?
It relaxes and moves upward, reducing thoracic volume.
29
Name the components of an alveolus.
Type I and Type II pneumocytes, alveolar macrophages, capillaries.
30
What forms the blood-air barrier?
Type I pneumocytes, endothelial cells, and a fused basal membrane.
31
Why does the epithelial lining of the respiratory tract change along the airway?
To accommodate different functions such as filtration, secretion, and gas exchange.
32
What structures form the upper respiratory tract?
Nasal cavity, pharynx, larynx.
33
What is the role of elastic fibers in the alveoli?
They help alveoli recoil during expiration.
34
What are the alveolar sacs?
Clusters of alveoli where gas exchange occurs.
35
Match the cell type to its function: Type I pneumocytes, Type II pneumocytes, Alveolar macrophages.
Type I: gas exchange, Type II: surfactant production, Macrophages: pathogen clearance.
36
Which part of the nasal cavity contains olfactory cells?
The olfactory region.
37
Why do smokers have more goblet cells in the bronchioles?
To compensate for increased particle exposure and lack of cilia due to damage.
38
Fill in the blank: The conducting portion of the respiratory system is responsible for ______.
Air conditioning
39
Name the components of the respiratory portion.
Respiratory bronchioles, alveolar ducts, alveoli.
40
What is the diameter of an alveolus?
Approximately 200 µm.
41
Describe the role of goblet cells in the respiratory epithelium.
They secrete mucus to entrap particles and microorganisms.
42
How does the nasal cavity condition air?
Warming, moistening, removal of particles (filtration).
43
What are the two primary functions of the nasal cavity?
Air conditioning and olfaction.
44
What is the structural role of C-shaped hyaline cartilage in the trachea?
It prevents the collapse of the trachea.
45
What type of immune tissue is associated with the respiratory epithelium?
MALT (mucosa-associated lymphoid tissue) and BALT (bronchus-associated lymphoid tissue).
46
Which muscles are primarily responsible for inhalation?
Diaphragm and external intercostal muscles.
47
What is the role of the respiratory epithelium?
It facilitates gas exchange and protects the airway by trapping and removing particles.
48
What is anosmia?
Loss of the sense of smell.
49
Why do bronchioles lack cartilage?
To allow flexibility and dynamic changes in airway resistance.
50
How do alveolar macrophages contribute to lung function?
They remove debris and pathogens from the alveoli.
51
What is the primary role of the respiratory portion of the respiratory system?
Gas exchange.
52
True or False: The nasal vestibule plays no role in filtration.
False, it acts as the first filter to entrap large particulate.
53
What are the four paired air-filled spaces surrounding the nasal cavity called?
Paranasal sinuses.
54
Describe the progression from terminal bronchioles to alveoli.
Terminal bronchioles → respiratory bronchioles → alveolar ducts → alveoli.
55
What is the primary cause of nasal hemorrhages?
Damage to the rich vascular bed of the lamina propria.