respiratory system Flashcards
what are the functions of the respiratory system
- respiration
- conditioning of air
- vocalisation
- sense of smell
- endocrine functions
- coughing and sneezing
- protection
- fibrinolysis
what are the parts of the conducting portion
- nasal cavity
- nasopharynx
- larynx
- trachea
- bronchi
- bronchioles
- terminal bronchioles
what are the parts of the respiratory portion
- respiratory bronchioles,
- alveolar ducts,
- alveolar sacs
- alveol
what does the wall of the conducting portion consist of
- mucosa
- submucosa
- fibre-cartilage layer
- adventitia
what are the 3 types of mucosa
- respiratory epithelium - pseudostratified columnar cilliated
- lamina proprica - loose connective tissue, secretes IgA
- muscularis - smooth muscle tissue - promise when airway diameter decreases
what is submucosa
loose connective tissue with mucous and serous glands
- not present beyond tertiary bronchi
what is fibro-cartilage
diminishes as the diameter of airway decreases
- not present beyond tertiary bronchi
what is adventitia
loose connective tissue
what does the respiratory epithelium consist of
- ciliated columnar cells - abundant type
- mucous goblet cells
- brush cells - microvilli, receptor cells for nerve endings from trigeminal and vagus nerves forming epitheliodendritic synapses
- basal short cells - lie on basal lamina and differentiate
- small granule cells - diffuse neuroendocrine system
what are goblet cells
- unicellular glands that produce mucinogen
- store mucinogen in secretary vesicles in the theca
- lower part is called the stem containing most organelles
what happens when mucinogen is released
released into lumen where it becomes hydrated into mucin and is mixed to form mucus
what is the function of cilia
transported mucus from bronchioles towards the pharynx and nasal cavity where it is swallowed or expelled
what is the composition of mucus
- hypophase - lower less dense layer with greater serous component
- epiphase - upper more dense layer - greater mucus component
what is mucostasis
retention and build up of mucus in respiratory tract
what is allergic rhinitis
caused by the release of histamines from mast cells with IgE after contact with allergen
that do histamines do to the respiratory tract
capillaries in nasal mucosa to dilate and increase permeability causing fluid to leave and enter the extracellular matrix leading to edema
what are the 3 regions of the nasal cavity
- nasal vestibule
- respiratory region
- olfactory region
what is the nasal vestibule
dilated space in nasal cavity just inside nostrils and is lined by skin with vibrisae
what is the respiratory region of the nasal cavity
largest part and is lined with respiratory mucosa
what is the olfactory mucosa
located at the apex of nasal cavities and is lined by specialised olfactory mucosa
- has smell receptors
- olfactory epithelium is yellow colour
what are the cells of olfactory epithelium
olfactory receptor cells - bipolar neurone
supporting columnar cells - support and electrical insulation
- basal cells - stem cells that differentiate into globose and horisontal cells
- brush cells
what is lamia propria
- deep in olfactory epithelium
- connective tissue with blood and lymphatic capillaries and olfactory nerve bundles
- olfactory (Bowmans) glands - branched tubuloalveolar serous glands
what is the cavernous layer
rich vascular plexus layer
- heat inspired air- prevent mucosa drying out and allows regeneration of epithelium
what are paranasal sinuses
air filled spaces in bones of the walls of nasal cavity