Respiratory system Flashcards
VO2 max
maximum rate in which oxygen can be consumed, transported and utilised by the respiratory, cardiovascular and muscular systems
external respiration
process of drawing oxygen into the body and expelling carbon dioxide back into the environment
primary contributor to airflow resistance
airway diameter
boyle’s law
as volume increases, pressure decreases
fick’s first law of diffusion
gas moves from high to low concentration regions
proportional to concentration gradient
expiratory muscles
none at rest
respond to increase in demand (exercise, altitude, illness)
contribute to control of breathing rate
perfusion
transport of molecules to target tissues
purpose of capillaries being one endothelial layer thick
reduces diffusion distance
slows down blood flow to allow more time for gas exchange to happen
partial pressure
in a mixture of gases, is the pressure exerted by each individual gas molecule
henry’s law
the concentration of dissolved gas equals the partial pressure of the gas, multiplied by its solubility
low solubility of gas=
less gas exchange
tidal volume
the amount of air that moves in or out of the lungs with each respiratory cycle
minute ventilation, Ve
tidal volume x breathing frequency
inspiratory reserve volume
the amount of air that can be inhaled, above that of the normal tidal volume
expiratory reserve volume
the amount of air that can be expired, below that of normal tidal volume
residual volume
the volume of air that remains in the lungs after a forced, maximal exhalation
prevents lungs collapsing
gas exchange can always occur
capacities
the maximal volumes of air i the lung parenchyma (functional tissue) during a specific point in the respiratory cycle
inspiratory capacity
maximal volume of air that can be inspired following a normal passive expiration
inspiratory reserve volume + tidal volume
functional residual capacity
volume of air in the lungs following a normal passive expiration (expiratory reserve volume + residual volume)
forced vital capacity
the total volume of air that can be expired following a maximal inspiration
inspiratory capacity + expiratory reserve volume
total lung capacity
the total volume of air in the lungs following a maximal inhalation
inspiratory capacity + functional residual capacity
forced expiratory volume
the amount of air that can be expired within the first second of a maximally forced expiration, following a maximal inhalation
at rest, what is inspiration and expiration controlled by
brainstem (pons and medulla oblongata)
pneumotaxic centre (inspiratory centre)
apneustic centre (expiratory centre)
chemoreceptors
detect changes in oxygen or carbon dioxide
feeds back to the respiratory centres in brain
peripheral receptors (carotid and aortic)
emergency detection for low oxygen
carotid receptors provide rapid response
pH/CO2 detection system
central (extracellular portion of brain)
slower response
steady state control
reduction in partial pressure of carbon dioxide during exercise
ventilation increased to remove CO2
chemoreceptors in the peripheries respond
tidal volume increases
breathing frequency increases
facilitates gas exchange
capillary volume increases
what causes ventilatory limitation
altitude
lung disease, eg cystic fibrosis