Nervous system: Synapses Flashcards

1
Q

synapse

A

anatomically specialised junction between two neurones
can converge or diverge
0.2ms

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2
Q

excitatory synapse

A

generate excitatory post synaptic potential: membrane potential of post-synaptic neuron is brought closer to threshold (i.e., depolarised). graded potential generated

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3
Q

inhibitory synapse

A

generate an inhibitory postsynaptic potential: membrane potential of post-synaptic is either driven further from threshold (i.e., hyperpolarised) or stabilised at resting potential
made more negative

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4
Q

electrical synapse

A

electrical activity of the presynaptic neurone affects that of the postsynaptic neuron
pre and post synaptic cells connected by gap junctions

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5
Q

chemical synapse

A

neurotransmitters transmit the signal

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6
Q

active zones

A

release regions in which vesicles are docked on the presynaptic membrane

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7
Q

types of receptors in post synaptic neurone

A

ionotropic (ion channels)
metabotropic (G protein/second messenger signalling)

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8
Q

removal of neurotransmitter

A

diffusion of transmitter from cleft
degradation of neurotransmitter by enzymes
reuptake into presynaptic cells for re use

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9
Q

why are multiple excitatory postsynaptic potentials needed

A

one=0.5mV
need a change of 15mV
not enough to reach threshold

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10
Q

temporal summation

A

repeated stimulation of one neurone

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11
Q

spatial summation

A

multiple neurones activated simultaneously to produce graded potentials
inhibitory synapses can also do this

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12
Q

muscle spindle

A

stretch receptors consist of peripheral endings of afferent nerve fibers wrapped around modified muscle fibers enclosed within a connective tissue capsule

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13
Q

intrafusal fibres

A

specialised muscle fibres to detect changes in stretch

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14
Q

extrafusal fibres

A

generate force, bulk of muscle

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15
Q

what does tension depend on

A

muscle length
load
fatigue

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16
Q

golgi tendon organs

A

endings of afferent nerve fibers that wrap around collagen
bundles in the tendons near their junction with the muscle
action potentials triggered when muscle stretches/contracts

17
Q

electroencephalogram (EEG)

A

recording of brain electrical activity
patterns largely due to graded potentials

18
Q

alpha rhythm

A

associated with decreased levels of attention

19
Q

beta rhythm

A

attentive to external stimulus

20
Q

5 major divisions of sensory receptors

A

Mechanoreceptors – pressure / stretch
Thermoreceptors– cold / warmth
Photoreceptors – different ranges of light
Chemoreceptors – binding of chemicals to the receptor (smell, taste, pH, O2)
Nociceptors– painful stimuli, such as heat, tissue damage

21
Q

sensory receptors

A

specialised cells that generate graded potentials called
receptor potentials in response to a stimulus
ends of afferent neurons
and can convert stimuli into graded potentials
Stimuli opens ion channels directly or indirectly

22
Q

ion flux

A

results in a change in membrane potential which results in a local graded
potential (receptor potential)
A larger stimulus results in a
larger graded potential which
results in more frequent action
potentials

23
Q

receptive field

A

The area of the body that when stimulated, leads to activity in a particular afferent neuron

24
Q

coding

A

the conversion of a stimulus into a signal
that conveys the relevant information

25
Q

modality

A

type of stimulus

26
Q

adequate stimulus

A

A given receptor is particularly sensitive to one stimulus modality

27
Q

acuity

A

The precision for locating the
stimulus depends on convergence where greater convergence causes less acuity
A neuron responds vigorously
when stimulus is in the
middle of the receptive field-more receptors activated, more ATs

28
Q

lateral inhibition

A