Respiratory Sys Flashcards

1
Q

Pulse oxy limitations. 9

A

a. Measures oxygen saturation, not O delivery to tissues

b. Insensitive to hyperoxia.

c. Artificially increased by: Carboxyhemoglobin

d. Artificially decreased by: Intravenous dyes, opaque nail polish, and methemoglobin levels >1%

e. Unreliable when pulse signal is poor: Hypothermia, hypovolemia, shock, edema, movement artifact

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2
Q

Oxyhemoglobin dissociation curve, shifts to right 6

A

Right shift—ACE BATs right handed:

Decrease affinity of Hb for O 2 (facilitates unloading of O 2 to tissue).

Acid
CO2 (increase in co2)
Exercise
2,3-BPG
Altitude
Temperature (hyperthermia)

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3
Q

Peak Expiratory Flow Rate (PEFR)

A

Maximal flow rate generated during a forced expiratory maneuver

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4
Q

Forced vital capacity (FVC)

Forced expiratory volume in 1

A

a. Forced vital capacity (FVC): Maximum volume of air exhaled from the
lungs after a maximum inspiration
b. Forced expiratory volume in 1 second (FEV1): Volume exhaled during
the first second of the FVC maneuver

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5
Q

common symptoms of asthma 5

A

chronic Cough (>8w) , increased work of breathing, wheezing, breathlessness, chest tightness

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6
Q

when to step up or down in asthma treatment

A

treatment may be stepped down if asthma is well controlled for at least 3 months and is stepped up 1 or 2 steps if asthma is not well controlled or is very poorly controlled. An alternative to stepping up therapy is to first try one of the alternative options in the same step

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7
Q

BPD definition

A
  • premature birth, characterized by the need for oxygen supplementation >21% for at least 28 days after birth
  • Pulmonary barotrauma and oxygen toxicity with subsequent inflammation of lung tissue due to ventilation of the immature lung (ventilation for more than 28 days)
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8
Q

Risk factors for BPD 6

A

Prematurity, IUGR, maternal smoking, perinatal infection,
mechanical ventilation, supplemental oxygen requirement

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9
Q

Treatment of BPD 8

A

Bronchodilators, antiinflammatory agents (corticosteroids), oxygen therapy, diuretics, tracheostomy
and prolonged mechanical ventilation for severe cases

increased caloric needs, carefully monitor
fluid status

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10
Q

Complication due to BPD

A

Pulmonary or systemic hypertension,
electrolyte abnormalities, nephrocalcinosis (from chronic diuretics),
neurodevelopmental or growth delay, sleep-disordered breathing,
aspiration from dysphagia and/or GER, more severe infections with RSV
or influenza

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11
Q

Risk factors for S. bronchiolities 4

A

age less than 12 weeks, a
history of prematurity, underlying cardiopulmonary disease, or
immunodeficiency

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12
Q

(sweat chloride) test: False-positive results can be seen in. 8

A

untreated adrenal insufficiency, glycogen storage disease type 1,
hypothyroidism, nephrogenic diabetes insipidus,
malnutrition, mucopolysaccharidosis, and panhypopituitarism.

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13
Q

Test to know if px has CF 3

A
  • newborn screening
  • sweat Chloride test
  • CFTR genetic analyis
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14
Q

GU complication in CF px. 4

A

-Nephrolithiasis,
-Men: usually infertile
The vas deferens may be absent.
Undescended testicle
-Women: reduced fertility
Viscous cervical mucus can obstruct fertilization.
Menstrual abnormalities (e.g., amenorrhea)
-Delayed development of secondary sexual characteristics in both men and women

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15
Q

OSA definition

A

obstruction of the upper airways due to the collapse of the pharyngeal muscles during sleep

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16
Q

OSA Presnetation. 7

A

snoring
increased respiratory effort during sleep,
sleepwalking,
enuresis,
ADHD
cardiac dysfunction,
systemic & pulmonary hypertension

17
Q

OSA Risk factors 9

A

Adenotonsillar hypertrophy, obesity, family history of OSAS,
craniofacial or laryngeal anomalies, prematurity, nasal/pharyngeal
inflammation, cerebral palsy, neuromuscular disease

18
Q

History in Px with OSA. 11

A

-Frequent snoring (≥3 nights/week)
-Labored breathing during sleep
-Gasping/snorting noises or observed episodes of apnea
-Mouth breathing
-Sleep enuresis (especially secondary enuresis)
-Sleeping in a seated position or with the neck hyperextended
-Cyanosis
-Headache on awakening
-Daytime sleepiness
-Attention-deficit/hyperactivity disorder
-Learning problems

19
Q

PE is OSA 7

A

-Underweight or overweight
-Tonsillar hypertrophy
-Adenoidal facies
-Micrognathia/retrognathia
-High-arched palate
-Failure to thrive
-Hypertension

20
Q

treatment for OSA

A

-Adenotonsillectomy
- Watchful waiting for up to 6 months can be considered for otherwise
healthy children with mild/moderate OSAS along with supportive care
(sleep hygiene practices, nasal saline spray, treatment for allergies)
-Intranasal corticosteroids or Oral leukotriene inhibitor

21
Q

DDX for BRUE

A
  • GER
  • Seizure
  • abuse/ Trauma
  • LRTI
  • Arrhythmia
  • in born error of metabolism
22
Q

High Risk BREU 8

A
  • age <2m
  • Required CPR
  • Event lasted >1min
  • more than 1 event of BRUE
  • Premature (<32w)
  • symptomatic at time of evaluation
  • significant physiologic compromise at the time of event
  • Dysmorphic features or suspected congenital syndrome
23
Q

Definition of BRUE

A

infant younger than 1 year with sudden, brief (<1 minute), and now-resolved episode of at
least one of the following:
1. Cyanosis or pallor
2. Absent, decreased, or irregular breathing
3. Marked change in tone (hyper- or hypotonia)
4. Altered level of responsiveness

24
Q

most appropriate treatment of first acquisition of Pseudomonas in CF px

A

inhaled antipseudomonal antibiotic, usually tobramycin + azithromycin

25
Q

Signs of sever Respiratory Distress 9

A

*Tachycardia
* Gasping
* Head bobbing
* Inability to speak
* Cyanotic, pale
* Quiet or agitated
* Hypoxic, even with
oxygen
* Chest may be silent
* Consciousness may be
impaired

26
Q

Signs of moderate Respiratory Distress 4

A
  • Tachypnea
  • Recessions are moderate
    or severe
  • Struggles to feed
  • Cannot speak in full
    sentences