Respiratory: Sleep Apnoea Flashcards

1
Q

Define what is meant by obstructive sleep apnoea [1]

A

Obstructive sleep apnoea is caused by complete or partial collapse of the pharyngeal airway during sleep. Apnoeas are episodes where the person stops breathing for up to a few minutes

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2
Q

What are the risk factors for sleep apnoea? [10]

A

obesity: – narrows upper airway
male sex: longer pharyngeal airway
post-menopause (women)
large neck circumference: increases risk
especially if greater than 16.5 inches
maxillomandibular anomalies (e.g., narrowing, retrognathia, and high, arched palate): micrognathia
increased volume of soft tissues (includes tonsils, adenoids, and tongue)
family history of OSA
chronic snoring
polycystic ovary syndrome (PCOS)
hypothyroidism
Down’s syndrome
increasing age
black, Hispanic, or Asian ethnicity
tobacco smoking

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3
Q

How do patients with sleep apnoea present? [6]

A

Episodes of apnoea during sleep (reported by a partner)
Snoring
Morning headache
Waking up unrefreshed from sleep
Daytime sleepiness
Concentration problems
Reduced oxygen saturation during sleep

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4
Q

What is the difference between apnoea and hypopnoea? [2]

A

Apnoea – a complete cessation of airflow for
at least 10 seconds

Hypopnoea – a reduction in airflow to under
50% or by 30% for at least 10 seconds with a desaturation of at least 4%

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5
Q

What is Apnoea and Hypopnoea Index? [1]

What are normal, mild, moderate and severe scores? [4]

A

AHI – number of apnoeas and hypopnoeas
per hour of the study

  • 0 to 5 Within normal limits
  • 5 to 15 Mild OSA
  • 15 to 30 Moderate OSA
  • 30 plus Severe OSA
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6
Q

What is micrognathia? [1]
Why does it increase chance of sleep apnoea? [1]

A

Micrognathia: condition in which the lower jaw is undersized

Micrognathia increases the risk of obstructive sleep apnea in children because the small size of the jaw narrows the airway and reduces the space needed for breathing

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7
Q

Why does obesity cause sleep apnoea? [1]

A

Fat deposition in the tissues surrounding the upper airway appears to result in a smaller lumen and increased collapsibility of the upper airway, predisposing to apnea.

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8
Q

Name 4 conditions that cause sleep apnoea due to the abnormal anatomy they cause [4]

A
  • Micrognathia or retrognathia
  • Large adenoids and tonsils
  • Acromegaly
  • Down’s syndrome
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9
Q

Name 4 systemic, associated conditions to sleep apnoea? [4]

A

Hypothyroidism
Cushing’s syndrome
Type II diabetes
Hypertension

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10
Q

What is the name for the sleep score used for measuring sleep apnoea?

What score is abnormal?
What is the total score

A

Epworth sleepiness scale
10 / 24 is abnormal

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11
Q

State 7 treatments that could be useful for sleep apnoea [7]

A
  • Weight loss
  • Avoiding alcohol and sedatives
  • Non-supine sleep
  • Tonsillectomy
  • Mandibular advancement splints
  • Palatal surgery
  • Maxillofacial surgery
  • Treat medical cause e.g. Cushings
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12
Q

What is this? [1]

When is it indicated? [1]

A

Mandibular splint
If CPAP not tolerated

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13
Q

What severity of sleep apnoea is CPAP indicated in? [2]

A

Continuous Positive Airway Pressure (CPAP):
Causes continous air passage to be open
Used for patients with moderate or severe sleep apnoea

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14
Q

Name three conditions that cause macroglossia and therefore sleep apnoea [3]

A

acromegaly, hypothyroidism, amyloidosis

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15
Q
A
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16
Q

What is the most common surgery for sleep apnoea? [1]

A

Surgery is an option but involves significant surgical reconstruction of the soft palate and jaw. The most common procedure is called uvulopalatopharyngoplasty (UPPP).

17
Q

A 61-year-old male snores at night, and his wife reports it is so loud that he often wakes her up. She notes that her husband sometimes appears not to take a breath for a long time and then gasps for air before continuing to snore. He suffers from daytime headaches and sleepiness. He has a body mass index (BMI) of 40 kg/m2.

What would the most likely arterial blood gas result be if it was measured in this patient?

Compensated respiratory acidosis
Compensated respiratory alkalosis
Compensated metabolic acidosis
Uncompensated respiratory acidosis
Uncompensated metabolic acidosis

A

Compensated respiratory acidosis

18
Q

Describe what hypoglossal nerve stimulation is [1]
How does it work? [1]

A

Hypoglossal nerve stimulation aims to treat obstructive sleep apnoea by preventing the tongue prolapsing backwards and causing upper airway obstruction during sleep. It works by delivering an electrical current to the hypoglossal nerve