Respiratory: Pneumonia I Flashcards

1
Q

What are the localised symptoms of pneumonia? [5]

What are the systemic symptoms of pneumonia? [3]

A

To be diagnosed with pneumonia, patients need to be suffering from:

Localised:
- Cough: productive or non-productive
- Dysopnoea
- Tachyopneoa
- Pleuritic chest pain
- Haemoptysis

Systemic:
- Sweating / Fever
- Weight loss: decreased appetite
- Confusion
- Fever > 38

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2
Q

What are the signs of pneumonia from examination? [3]

A

Bronchial breath sounds (harsh inspiratory and expiratory breath sounds) due to consolidation around the airways

Focal coarse cracklescaused by air passing through sputum in the airways

Dullness to percussion due to lung tissue filled with sputum or collapsed

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3
Q

What are the non-examination signs of pneumonia? [3]

A
  • Tachypnoea, Tachycardia
  • Hypoxia
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4
Q

D

Describe how you assess the severity of pneumonia [5]

A

Within hospital:
C – Confusion (new disorientation in person, place or time)
U – Urea > 7 mmol/L
R – Respiratory rate ≥ 30
B – Blood pressure < 90 systolic or ≤ 60 diastolic.]
65 – Age ≥ 65

NB Community: CRB-65

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5
Q

What CURB-65 scores would indicate:

Treatment at home [1]
Admission [1]
Intensive care [1]

A

Score 0/1: Consider treatment at home
Score ≥ 2: Consider hospital admission
Score ≥ 3: Consider intensive care

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6
Q

Which infective organisms are most likely to cause CAP? [3]

A

Streptococcus pneumonia; - 1st
Haemophilus influenzae; Staphylococcus aureus;

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7
Q

Which type of organisms are most likely to cause HAP? [1]

Which infective organisms are most likely to cause HAP? [4]

A

Gram negative organisms:

PEKA:
Pseudomonas aeruginosa,
Escherichia coli
Klebsiella pneumoniae
Acinetobacter species.

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8
Q

What are the features that would make pneumonia atypical? [4]

A
  • symptoms may be subacute or less severe hence the term ‘walking pneumonia’
  • absence of lobar consolidation on chest x-ray
  • not detectable on Gram stain
  • lack of response to penicillin antibiotics
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9
Q

Which organisms are most likely to cause atypical pneumonias?

A

TOM TIP: You can remember the 5 causes of atypical pneumonia with the mnemonic: “Legions of psittaci MCQs”:

Legions: Legionella pneumophila
Psittaci: Chlamydia psittaci
M – Mycoplasma pneumoniae
C – Chlamydophila pneumoniae
Qs – Q fever (coxiella burnetii)

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10
Q

Atypical pneumonias:

Which type of pneumonia occurs from inhaling infected water from infected water systems, such as air conditioning units? [1]

A

Legionella pneumophila (Legionnaires’ disease)

The typical exam patient has recently had a cheap hotel holiday and presents with pneumonia symptoms and hyponatraemia

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11
Q

Describe the pathological consequences of Legionella pneumophila [2]

A

Causes SIADH: results in hyponatraemia

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12
Q

Describe the clinical presentation of Legionella pneumonia [5]

A
  • high fever
  • chills
  • malaise
  • non-productive cough
  • dyspnea
  • pleuritic chest pain.
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13
Q

How do you detect Legionella infection? [1]

A

Legionella urinary antigen

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14
Q

Comparison of Legionella and Mycoplasma pneumonia

Name three distinguishing features of Leginella pneumonia that would differentiate from Mycoplasma pneumonia

A

Hyponatramia (from SIADH)
Lymphopenia
Diagnosis via urinary antigen

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15
Q

Which drug do you use to tx Legionellas? [1]

A

With erythromycin/clarithromycin

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16
Q

Describe the clinical features of Mycoplasma pneumonia [3]

A
  • prolonged and gradual onset
  • Erythema multiforme RASH: effects 1/3rd of patients on trunks and limbs
  • flu-like symptoms ( classically PRECEED a dry, persistent cough
  • bilateral consolidation on x-ray
17
Q

Name and describe the rash exhibited by Mycoplasma pneumoniae [2]

A

erythema multiforme:
- Target lesions: pink rings and pale centres

18
Q

Describe ascultation findings of Mycoplasma pneumonia [1]

A

Coarse crackles will CHANGE to fine crackles at a late phase (3-5 days after initial onset).

19
Q

If an atypical pathogen such as Mycoplasma pneumoniae is suspected, it is best to confirm the diagnosis using a [] ?

A

If an atypical pathogen such as Mycoplasma pneumoniae is suspected, it is best to confirm the diagnosis using a NAAT: e.g., polymerase chain reaction [PCR] on nose and throat swabs

20
Q

State 4 clinical consequences of untreated Mycoplasma pneumonia [4]

A

Haemolytic anaemia
Erythema multiforme
Encephalitis
Peri / myocarditis

21
Q

How do you treat Mycoplasma pneumonia? [2]

A

1st line:Erythromycin OR Clarithromycin

2nd line: Doxycycline or a macrolide (e.g. )

Because generally there is no diagnosis of the pathogen at the time of treatment, initiation of the treatment is usually empirical

BMJ BP

22
Q

Mycoplasma pneumonia may cause what haematological consequence? [1]

A

haemolytic anaemia

23
Q

State and describe this complication of Mycoplasma pneuomia [2]

A

bullous myringitis: painful vesicles on the tympanic membrane

24
Q

Which infective organsim causing atypical pneumonia is linked to exposure by bodily fluids of animals? [1]

A

Coxiella burnetii, or Q fever, is linked to exposure to the bodily fluids of animals. The typical exam patient is a farmer with a flu-like illness.

25
Q

Atypical pneuomonia

[] is typically contracted from contact with infected birds. The typical exam patient is a parrot owner.

A

Chlamydia psittaci is typically contracted from contact with infected birds. The typical exam patient is a parrot owner.

26
Q

Which infective organism causes pneumonias in immunocompromised patients? [1]

A

Pneumocystis jirovecii

Patients with poorly controlled HIV and a low CD4 count are particularly at risk

Pneumocystis jirovecii pneumonia (PCP)

27
Q

How does PCP usually present? [5]

Pneumocystis jirovecii pneumonia (PCP)

A

dyspnoea
night sweats
dry cough
fever
very few chest signs
Pneumothorax is a common complication of PCP.

28
Q

What drug is used as prophylaxis [1] and to treat [1] PCP?

A

Treatment:
- Co-trimoxazole

Prophylaxis:
- co-trimoxazole

29
Q

What clinical presentation may indicate COVID caused pneuomonia? [1]

A

Silent hypoxia: Patients may not feel particularly short of breath despite having low oxygen saturations

30
Q

What is important to know about the most common cause of pneumonia? [1]

A

Most common KNOWN cause is Strep. pneumonie;

But in a greater number of cases there is no pathogen identified

31
Q

what is HAP definition with regards to timings? [2]

A

HAP = Inpatient > 48hrs or less than ten days post discharge

32
Q

Elderly patients are less likely to suffer pneumonia from which two pathogens? [2]

A

Mycoplasma pneumoniae
Legionella

33
Q

Describe which type of bacteria alcoholics are most likely to get pneumonia from [1]

A

Risk of aspiration pneumonia; anaerobic pathogens have increased chance

34
Q

HIV / AIDs patients are more likely to suffer from which infective organisms that cause pneumonia? [2]

A

TB
PCP

35
Q

Chemotherapy patients are more likely to suffer pneumonia from what group of infective agents? [1]

A

Fungal

36
Q
A