respiratory failure Flashcards
what is the drive for breathing?
medulla receptor, respond to CO2 and pH
what is the equation for [A-a]O2 gradient?
= [(FiO2) x (Patmos – PH2O) – (PaCO2 / RQ) – PaO2]
what could cause low oxygen delivery?
altitude, hypobaric chamber
what could cause airways obstruction?
asthma, COPD
what could causes diffusion limitation?
lung fibrosis, asbestosis
what could cause ventilation/perfusion mismatch?
pneumonia
pulmonary embolism
pulmonary hypertension
what could cause alveolar hypoventilation?
emphysema
muscular weakness (MND)
reduced respiratory drive (opiates)
obesity
what might cause T2 resp failure?
airways obstruction (asthma, COPD) alveolar hypoventilation emphysema muscular weakness (MND) reduced respiratory drive (opiates) obesity)
what is type 1 resp failure?
low oxygen, low or normal CO2, normal HCO3
what can cause T1 resp failure?
pneumonia, pulmomnary embolism
what is type 2 resp failure?
low oxygen
high CO2
high HCO3, normal is acute