pulmonary arterial hypertension

Question 1

what is the epidemiology of pulmonary arterial hypertension?

Answer 1

A rare, frequently fatal disease, most commonly seen in women

Question 2

how does pulmonary arterial hypertension present?

Answer 2

non-specific and include dyspnoea on exertion, fatigue, and a loud pulmonary component of the second heart sound.

Question 3

how is pulmonary arterial hypertension managed?

Answer 3

General supportive therapy includes oral anticoagulants, diuretics, supplemental oxygen, and digoxin.

Targeted treatment options include parenteral, inhaled, and oral prostanoids, oral endothelin receptor antagonists, oral phosphodiesterase type-5 inhibitors, the soluble guanylate cyclase stimulator riociguat, and the selective prostacyclin IP receptor agonist selexipag.

Question 4

what do most patients commonly develop from pulmonary arterial hypertension?

Answer 4

right ventricular heart failure