Respiratory Embryology Flashcards

1
Q

What action gives rise to the primitive gut tube?

A

Folding

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2
Q

The trachea and lungs form from what?

A

Foregut

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3
Q

What is the name of the median outgrowth from the ventral foregut?

A

Laryngotracheal groove (diverticulum)

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4
Q

What forms between the trachea and oesophagus to separate them?

A

Oesophagotracheal septum

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5
Q

What is a fistula? What is common in the respiratory system?

A

Abnormal/surgical passage made between two tubular organs

tracheoesophageal fistula common

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6
Q

Atresia is what?

A

Condition in which a passage is closed or absent

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7
Q

The visceral pleura is formed of what?

A

Splanchnic mesoderm

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8
Q

The parietal pleura is formed of what?

A

Somatic mesoderm

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9
Q

The gap between the parietal and visceral pleura is called what?

A

Pleuroperitoneal canals

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10
Q

What are the pleuroperitoneal folds?

A

Folds forming around the heart separating pleural and pericardial cavities

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11
Q

Sequence of differentiation of lung buds

A
Embryonic
Pseudoglandular
Canalicular
Saccular
Alveolar
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12
Q

Common congenital conditions of the lungs

A

Surfactant deficiency
Accessory lobe
Lung agenesis
Lobe of azygos vein

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13
Q

Which 4 embryonic components form the diaphragm?

A

Septum Transversum
Pleuroperitoneal membranes
Dorsal mesentery of oesophagus
Muscular ingrowth from lateral body walls

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14
Q

Septum Transversum forms what?

A

Central tendon of the diaphragm

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15
Q

The Pleuroperitoneal membranes form what?

A

Primitive diaphragm

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16
Q

The Dorsal mesentery of oesophagus forms what?

A

Median portion of diaphragm

Crura of diaphragm

17
Q

Muscular ingrowth from lateral body walls forms what?

A

Peripheral diaphragm

18
Q

Where is septum transversum intially located? Which way does it migrate?

A

C3-C5 somites

Migrates caudally

19
Q

3 major defects in congenital diaphragm disorders?

A

Failure of diaphragm to close
Herniation into chest
Pulmonary hypoplasia

20
Q

What are the diaphragmatic hernias?

A

Incomplete development of the diaphragm
Posterolateral
Anterior
Central

21
Q

What are hiatus hernias?

A

Bulging of the stomach into the chest through the oesophageal hiatus

22
Q

What are the two types of hiatus hernia?

A

Sliding

Paraesophageal

23
Q

What structure forms the central tendon?

A

Septum transversum

24
Q

What structure forms the crura and medial portion of the diaphragm?

A

Dorsal mesentery

25
Q

What structure forms the primitive diaphragm?

A

Pleuroperitoneal membranes

26
Q

What structure forms the peripheral diaphragm?

A

Muscular ingrowth from the lateral body walls