Respiratory Embryology Flashcards
where does the epithelium of the resp system develop from?
nasal cavity epi from ectoderm
rest is from endoderm
laryngotracheal groove
beginning of larynx, trachea, and lungs
evagination of endoderm along floor of pharynx
tracheoesophageal septum
grows from lateral walls of laryngotracheal groove and fuses along midline
larygotracheal tube
created by septum
separate from esophagus
future trachea and lung buds
larynx development
develops rostrally
lumen of groove retains communication with pharynx
laryngeal swellings
bilateral on laryngeal opening
give rise to cartilage of the larynx
from pharyngeal arch splanchnic mesoderm
laryngeal muscles
from somite myotomes that migrate into pharyngeal arches
developing trachea and lungs
LT tube grows caudally
bronchi shifted into splanchnic mesoderm which contributes cartilage and ct
endoderm gives resp epithelium
principal bronchi development
blind caudal end of LT tube develops bi lobed bronchial buds which outgrow to create lobar bronchi, segmental bronchi, bronchioles with alveoli
lung development
endoderm lined brachial tree
splanchnic mesoderm forms fascia and cartilage
branches initially solid but terminal branches become hollow with thin epi
septae partition terminal sacs to make alveoli