Respiratory Drugs Flashcards
Oxygen Class
Element
Oxygen Actions
Oxidises glucose to produce ATP
Oxygen Indications
Hypoxia, CP, Hypoperfusion, Resp. insufficiency, CO poisoning
Oxygen Contraindications
none
Oxygen Adult Dose
Hi: 10-15 lpm/nrb Lo: 1-4 lpm/nc
Oxygen Ped Dose
Hi: 10-15 lpm/nrb Lo: 1-4 lpm/nc
Oxygen SE
decreased LOC and respiratory depression in pt with chronic CO2 retention
Albuterol Class
Sympathomimetic, bronchodialator, β2-agonist
Albuterol Actions
lung smooth muscle relaxant, bronchodialation
Albuterol Indications
relief or prevention of bronchospasm
Albuterol Contraindications
tachycardic dysthrythmia
Albuterol Adult Dose
2.5 mg / neb; up to 3x
Albuterol Pediatric Dose
0.1 mg/kg neb; up to 3x
Albuterol SE
restlessness, dizzziness, palpitations, tachycardia, dyrythmia, angina
Abuterol brand name
Proventil
Ipatroprium Bromide class
Anticholinergic bronchodialator
Ipatroprium Bromide actions
inhibits acetylcholine at receptor sites on bronchial smooth muscle
Ipratroprium Bromide Indications
persistent bronchospasm, COPD
Ipratroprium Bromide adult dose
500 ug up to 3x
Ipratroprium Bromide pediatric dose
125-250 ug up to 3x
Ipratroprium Bromide SE
N/V, Coughing, HA, Tachycardia, dry mouth, blurred vision
Ipratroprium Bromide brand name
Atrovent
Methylprednisolone actions
supresses inflammation;β-adrenergic agonist vascular smooth muscle relaxant
Methylprednisolone indications
Anaphylaxis, unresponsive asthma
Methylprednisolone contraindications
caution with GI bleed, diabetes mellitus, severe infection
Methylprednisolone adult dose
125 mg IV/IM
Methylprednisolone pediatric dose
2 mg/kg IV/IM up to 125 mg
Methylprednisolone SE
HA, HTN, Na+ and H20 Retention, Hypokalemia, Alkalosis
Methylprednisolone brand name
Solu-Medrol
Metaproterenol class
Sympathomimetic / adrenergic bronchodialator
Metaproterenol indications
acute asthma, COPD Bronchospasm
Metaproterenol contraindications
hs
Metaproterenol actions
relaxes smooth muscles of the bronchial treee & peripheral vasculature
Metaproterenol adult dose
2-3 inh/3-4h -OR- 10-15 mg 5% / neb / q4-6h
Metaproterenol pediatric dose
2-3 inh/3-4h -OR- 0.5-1 mg/kg 5% / neb / q4-6h
Metaproterenol SE
restlessness, dizzziness, palpitations, tachycardia, dyrythmia, angina, n/v, PE
Metaproterenol brand name
Aluepent
Aminophylline class
Xanthine bronchodialator
Aminophylline actions
lung smooth muscle relaxant, bronchodialation
Aminophylline indications
Acute Bronchospasm, Acute Asthma, Anaphylaxis, apnea
Aminophylline contraindications
hs to caffeine
Aminophylline adult dose
5mg/kg IV/20-30 min –> 0.5-0.8 mg/kg/hr
Aminophylline pediatric dose
5mg/kg IV/20-30 min –> 0.5-0.8 mg/kg/hr
Aminophylline SE
restlessness, sz, tachycardia, flushing, hypotension, n/v
Aminophylline brand name
Quibron & Theodur
ipratroprium contraindications
hs
methylprednisolone class
synthetic glucocorticosteroid
terbutaline class
Sympathomimetic / adrenergic agonist
terbutaline actions
stimulates β2 adrenergic receptors, relaxes uterine and smooth muscle, relieves bronchospasm
terbutaline indications
acute asthma, COPD Bronchospasm, delays labor
terbutaline contraindications
hs to sympathomimetics
terbutaline adult dose
Bronchospasm: 0.25 mg SQ/rpt in 15-30m -OR- 1mg/3ml neb
preterm labor: 2.5 - 10 mcg/min IV infusion/increase up to 30 mcg/min
terbutaline pediatric dose
NR
terbutaline SE
HA, restlessness, dizzziness, palpitations, tachycardia, dyrythmia, n/v, heartburn
terbutaline brand name
Brethine
epi 1:1000 class
Sympathomimetic / natural catecholamine
epi 1:1000 actions
α - effects: vasoconstriction, bronchial arteriole constriction - reduced edema
β - effects - +HR, contractility, automaticity
epi 1:1000 indications
cardiac arrest, acute asthma, anaphylaxis, refractory adult brady, pediatric brady, pediatric non-hypovolemic shock
epi 1:1000 contraindications
narrow angle glaucoma, hypovolemia, HTN
epi 1:1000 adult dose
Asthma: 0.3 - 0.5 mg SQ q20m, IV in severe
Allergic Rx: 0.3 mg SQ q20m; IV slow if severe, poor perfusion, hypotension
epi 1:1000 pediatric dose
Asthma: 0.01 mg/kg SQ q20m
Allergic Rx: 0.01 mg/kg SQ up to 0.3 mg; IV slow if severe
epi 1:1000 SE
anxiety, HA, dysthrythmias, hyperglycemia
epi 1:1000 brand name
Adrenaline
Diphenhydramine class
antihistamine
Diphenhydramine actions
blocks histamine at H1 binder site, anticholinergic, sedative effect
Diphenhydramine indications
allergic reactions, anaphylactic shock
Diphenhydramine contraindications
nursing, pregnancy, acute asthma, MAOI w/in 2w
Diphenhydramine adult dose
25-50 mg IV slow, repeat to 100 mg total
Diphenhydramine pediatric dose
1-2 mg/kg IV very slow to 50 mg
Diphenhydramine SE
drowsiness, HA, NV, hypotension, dry membranes
Diphenhydramine brand name
benadryl
Respiratory and Allergic Reaction Drugs
Oxygen, Albuterol, Ipratroprium, Methylprednisolone, Aminophylline, Terbutaline, Epinephrine 1:1000, Diphenhydramine