Anticonvulsive Drugs Flashcards

1
Q

Diazepam Class

A

Benzodiazepine sedative / Anticonvulsant

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2
Q

Diazepam Actions

A

CNS depressant, elevates sz threshold, skeletal musc relaxant

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3
Q

Diazepam Indications

A

suppresion of sustained and/or recurrent grand-mal sz; sedation for cardioversion or acute anxiety

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4
Q

Diazepam Contraindications

A

respiratory depression; glaucoma

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5
Q

Diazepam Adult Dose / route

A

5-10 mg IV slow (less than 5 mg/60s) repeat in 10 minutes up to 30 mg.

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6
Q

Diazepam Pediatric Dose / route

A

0.1-0.3 mg/kg/IV slow , repeat ea 2 min to 1mg/kg. or PR @ 0.5 mg/kg half dose repeated at 10 min

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7
Q

Diazepam Side Effects

A

drowsiness, lethargy, hypotension, dysrhythmias

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8
Q

Diazepam brand name

A

Valium

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9
Q

Lorazepam class

A

Anticonvulsant / Sedative

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10
Q

Lorazepam actions

A

CNS depressant, elevates sz threshold, skeletal musc relaxant

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11
Q

Lorazepam indications

A

status epilepticus, sedation prn

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12
Q

Lorazepam contraindications

A

respiratory depression, glaucoma

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13
Q

Lorazepam adult dose / route

A

0.05 mg/kg IV slow up to 4 mg, repeat in 10-15 minutes

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14
Q

Lorazepam pediatric dose / route

A

none

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15
Q

Lorazepam side effects

A

anterograde amnesia, vertigo, hepatic dysfunction

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16
Q

Lorazepam brand name

A

Ativan

17
Q

Midazolam class

A

Benzodiazepine sedative

18
Q

Midazolam actions

A

CNS depressant; amnesiac

19
Q

Midazolam indications

A

premedication for cardioversion, emergent intubation

20
Q

Midazolam contraindications

A

respiratory depression due to drugs or CNS depression

21
Q

Midazolam adult dose / route

A

2-5 mg IV/slow, repeat prn

22
Q

Midazolam pediatric dose / route

A

0.03 mg/kg IV slow

23
Q

Midazolam side effects

A

amnesia, drowsiness, tachycardia, hypotension, N/V

24
Q

Midazolam brand name

A

Versed

25
Q

Flumazenil class

A

Benzodiazepine antagonist

26
Q

Flumazenil actions

A

inhibits actions of benzo… on the GABA-benzo… receptor complex

27
Q

Flumazenil indications

A

benzo- reverseal after anasthesia or sedation, or suspected benzo- OD

28
Q

Flumazenil contraindications

A

caution w/ HI, high risk of SZ

29
Q

Flumazenil adult dose / route

A

sedation reversal: 0.2 mg IV/15s, 60s intervals to 1 mg; OD: 0.2mg IV/30s, 60s intervals to 3 mg.

30
Q

Flumazenil pediatric dose / route

A

sedation reversal 0.01mg/kg IV/15s, continue ea 60s up to 0.05mg/kg or 1 mg; OD: none

31
Q

Flumazenil side effects

A

dizziness, blurred vision, HA, arrythmias, N/V

32
Q

Flumazenil brand name

A

Romazicon; Mazicon; Lanexat; Anexate