Drug use & dose

Question 1

Aminophylline

Answer 1

For bronchospasm; acute asthma; severe allergic rxns & anaphylactic shock; apnea:

Adults & Peds: 5 mg/kg IV over 20-30 minutes + 0.5-0.8 mg/kg/hr infusion.

Question 2

Ipratropium

Answer 2

bronchospasm due to COPD; Inhibits nasal secretions:

Adult inh: 2 inh x4/d up to 12/d
Adult neb: 500 mcg 3-4/d

Ped inh: 1-2 inh x3/d up to 6/d
Ped neb: 125-250 mcg 3/d

Question 3

Levalbuterol

Answer 3

to prevent or treat bronchospasm:

12-adult: 0.63 to 1.25 mg via neb ea 6-8h

Question 4

Metaproterenol

Answer 4

acute asthma; symptomatic relief of bronchospasm:

10-15 mg of 5% every 4-6h -or- 2-3 inh / 3-4h

Question 5

Terbutaline

Answer 5

acute asthma; bronchospasm/COPD; delays premature labor in pregnancies between 20-34 weeks:

bronchospasm: 0.25 mg SQ ea 15-30m prn -or- neb 1 mg/3ml NSS
preterm labor: 2.5-10 mcg/min IV up to 30 mcg/min

12-18 yo: 0.01 mg/kg up to 0.4 mg/dose ea 15-20 minutes for 2 doses