Respiratory Development Flashcards
what does TBX4 do in lung formation?
determines location of lung bud and induces formation
induces differentiation of lungs
Larynx, trachea, bronchi, and most of the lung epithelium is formed by what?
endoderm
connective, muscular, and cartilaginous tissue in the trachea and lungs is formed by what?
splachnic mesoderm
what separates the lung bud from the foregut?
2 tracheoesophageal ridges
what divides the foregut into a dorsal and ventral part?
tracheoesophageal septum
the larynx internal lining is derived from what?
endoderm
what do the cartilages and muscles of the larynx originate from?
4th and 6th pharyngeal arches
what are the 4th arch derivatives of the larynx innervated by?
superior laryngeal nerve
what are the 6th arch derivatives of the larynx innervated by?
recurrent laryngeal nerve
what is the space the lung buds expand into?
pericardioperitoneal canals
what 2 folds separate the pericardioperitoneal cavity into 3 spaces?
the pleuroperitonial
the pleuropericardial
Mature alveoli are present at birth- TRUE or FALSE?
FALSE
why is fetal breathing movements important before birth?
it conditions the muscles
stimulates lung development
esophageal atresia and tracheoesophageal fistulas are associated w/ VACTERL. What does that stand for?
vertebral abnormalities anal atresia cardiac tracheoesophageal fistulas esophageal hiatus renal anomalies limb defects
