Integumentary system Flashcards

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1
Q

what are the 2 layers of the integumentary system?

A

epidermis

dermis

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2
Q

what type of epithelium is the epidermis and what is it derived from

A

stratified squamous epithelium (keratinized)

ectoderm

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3
Q

what type of epithelium is the dermis and what is it derived from?

A

dense connective tissue

mesoderm

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4
Q

what is the layer beneath the dermis?

A

hypodermis

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5
Q

what are the 5 layers of the epidermis?

A
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum
Stratum corneum
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6
Q

how are cells of the stratum basale connected to the basal lamina?

A

hemidesmosomes

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7
Q

how are the cells of the stratum basale connected to each other?

A

desmosomes

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8
Q

what do the cells of the stratum basale contain?

A

melanin

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9
Q

what special process happens in the stratum basale because of the abundant o2 and nutrients?

A

mitosis

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10
Q

what special feature do the cells in the stratum spinosum have?

A

spines

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11
Q

how are the spines connected to adjacent cells?

A

desmosomes

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12
Q

what are the thickening of the desmosomes in the stratum spinosum called?

A

nodes of Bizzozero

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13
Q

what granules are in the cells of the stratum granulosum?

A

keratohyalin granules

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14
Q

what proteins/compounds are in the keratohyalin granules?

A

cysteine and histadine-rich proteins

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15
Q

what are cells of the stratum corneum filled w/?

A

keratin

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16
Q

what type of collagen makes up the papillary layer of the dermis?

A

type 1 and 3

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17
Q

what are dermal papillae?

A

protrusions into the epidermis= fingerprints

18
Q

what type of collagen/fibers make up the reticular layer of the dermis?

A

type 1 collagen + elastic fibers

19
Q

what do the type 1 collagen and elastic fibers of the reticular layer of the dermis form in the skin?

A

Langer’s lines

20
Q

what does excessive stretching of the reticular layer of the dermis cause?

A

stretch marks

21
Q

where are two examples of smooth muscle in the hypodermis?

A

arrector pili muscle (cause goose bumps around hair)

dartos muscle in scrotum

22
Q

what is the layer of adipose tissue of the hypodermis called?

A

panniculus adiposus

23
Q

what is the vestigual layer of striated muscle deep to the subcutaneous fascia in the hypodermis?

A

panniculus carnosus

24
Q

what 3 things do keratinocytes of the epidermis synthesize?

A

keratin
keratohyalin granules
lamellar bodies

25
Q

what are melanocytes derived from?

A

neural crest cells

26
Q

What is an epidermal-melanin unit?

A

Melanocyte+ a # of keratinocytes

27
Q

what is the most significant factor in skin color?

A

melanin content

28
Q

what enzyme is critical to produce melanin?

A

tyrosinase

29
Q

what are the most common characteristics in Waardenburg syndrome?

A

Patch of white hair and skin
Heterochromia irides (eyes of different colors)
Deafness

30
Q

what causes Waardenburg syndrome?

A

faulty proliferation/migration of neural crest cells

31
Q

what are 3 key features of Langerhans cell?

A

Part of the mononuclear phagocytic system
APC
Initiates cutaneous hypersensitivity

32
Q

what is Merkel’s corpuscle

A

Merkel’s corpuscle= neuron + Merkel cell

33
Q

what are Pacinian corpuscles

A

Deep pressure receptors

34
Q

what are Meissner’s corpuscles

A

Touch receptors (dermal papillae)

35
Q

what are Ruffini corpuscles

A

Mechanical displacement of collagen fibers

36
Q

How is the Sebaceous gland connected to the hair?

A

by the pilosebaceous duct

37
Q

what is the type of secretion that is used to secrete sebum?

A

holocrine

38
Q

what are eccrine sweat glands also called?

A

sudoriferous glands

39
Q

how is the excretory product discharged from apocrine sweat glands?

A

exocytosis

40
Q

what are the parts of the nail?

A
Root
Matrix
Lunula (white half moon)
Eponychium (cuticle)
Hyponychium (under the nail)
41
Q

what is the name of the eyelash mite?

A

Demodex folliculorum