Respiratory COPY Flashcards
1
Q
What is Goodpasture’s Syndrome?
A
- autoimmune anti glomerular basement membrane disease
- antibodies attack basement membrane in lungs and kidneys
- bleeding lungs, glomerulonephritis, kidney failure
2
Q
Presentation of Goodpasture’s
A
- haemoptysis
- haematuria
- dyspnoea
- glomerulonephritis
- chest pain
- fever
- fatigue
3
Q
Investigations for Goodpasture’s
A
lung and kidney biopsy → anti-GBM antibodies
4
Q
Treatment for Goodpasture’s
A
- supportive
- corticosteroids
- immunosuppresants
- removal/replacement of plasma → plasmapheresis
5
Q
What is hypersensitivity penumonitis?
A
- type 3 hypersensitivity reaction
- alveolar and bronchial inflammation after exposure to inhaled allergen
6
Q
Presentation of hypersensitivity
A
- dyspnoea
- cough
- fever
- malaise
- weight loss
7
Q
Investigations for hypersensitivity pneumonitis
A
bronchoalveolar lavage
- raised lymphocytes
- raised mast cells
8
Q
Treatment of hypersensitivity pneumonitis
A
- remove allergens
- steroids
9
Q
What are examples of occupational lung disorders
A
- silicosis
- asbestosis
- bird fanciers lung
10
Q
What is pharyngitis?
A
rapid onset of sore throat and pharyngeal inflammation +/- exudate
11
Q
Common causes of pharyngitis
A
- EBV
- adenoviruses
- enteroviruses
- group A streptococcus
12
Q
Symptoms of pharyngitis
A
- sore throat
- fever
- headache, nausea, abdominal pain → kids
- rhinorrhoea, nasal congestion, cough → viral
13
Q
What factors suggest a group A strep pharyngitis?
A
- pharyngeal exudates
- cervical adenopathy
- fever
- absence of cough/rhinorrhoea
14
Q
Diagnosis of pharyngitis
A
- clinical symptoms consistent with group A strep infection
- rapid antigen detection test for group A strep
- -ve → conventional throat culture
15
Q
Treatment of pharyngitis
A
- supportive → analgesia
- if group A strep, add Abs