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MD2 Pharmacology > Respiratory > Flashcards

Respiratory Flashcards

1
Q

Salbutamol class

A

B2 agonist

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2
Q

Salbutamol mechanism of action

A

Stimulates B2 adrenoceptors in bronchial smooth muscle resulting in relaxation and bronchodilation

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3
Q

Salbutamol: short- or long-acting?

A

Short

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4
Q

Salbutamol indications

A 
Acute asthma
Symptomatic relief during maintenance of asthma/COPD
Prevention of exercise-induced asthma
Management of preterm labour
Relief of bronchospasm in anaphylaxis
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5
Q

Salbutamol adverse effects

A 
Tremor
Palpitations
Headache
Hyperglycaemia (high dose)
Tachycardia
Muscle cramps
Agitation
Serious hypokalaemia (worsened by theophyllines/GCS)
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6
Q

Salbutamol contraindications

A

CVD (including HTN, IHD, CCF and arrhythmias)
Hyperthyroidism (due to CV risk)
DM (risk of hyperglycaemia)

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7
Q

Terbutaline class

A

B2 agonist

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8
Q

Terbutaline mechanism of action

A

Stimulates B2 adrenoceptors in bronchial smooth muscle resulting in relaxation and bronchodilation

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9
Q

Terbutaline: short- or long-acting?

A

Short

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10
Q

Terbutaline indications

A

Acute asthma
Symptomatic relief during maintenance of asthma/COPD
Prevention of exercise-induced asthma

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11
Q

Terbutaline adverse effects

A 
Tremor
Palpitations
Headache
Hyperglycaemia (high dose)
Tachycardia
Muscle cramps
Agitation
Serious hypokalaemia (worsened by theophyllines/GCS)
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12
Q

Terbutaline contraindications

A

CVD (including HTN, IHD, CCF and arrhythmias)
Hyperthyroidism (due to CV risk)
DM (risk of hyperglycaemia)

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13
Q

Salmeterol class

A

B2 agonist

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14
Q

Salmeterol mechanism of action

A

Stimulates B2 adrenoceptors in bronchial smooth muscle resulting in relaxation and bronchodilation

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15
Q

Salmeterol: short- or long-acting?

A

Long

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16
Q

Salmeterol indications

A

Maintenance of asthma in pts receiving inhaled/oral GCS

Maintenance of COPD

17
Q

Salmeterol administration

A

Can be co-administered in fixed dose combined inhaler with fluticasone (GCS)

18
Q

Salmeterol adverse effects

A 
Tremor
Palpitations
Headache
Hyperglycaemia (high dose)
Tachycardia
Muscle cramps
Agitation
Serious hypokalaemia (worsened by theophyllines/GCS)
19
Q

Salmeterol contraindications

A

CVD (including HTN, IHD, CCF and arrhythmias)
Hyperthyroidism (due to CV risk)
DM (risk of hyperglycaemia)

20
Q

Tiotropium class

A

Anticholinergic

21
Q

Tiotropium administration

A

Dry powder inhaler (18mg)

22
Q

Tiotropium mechanism of action

A

Blocks muscarinic actions of ACh, inhibiting cholinergic bronchomotor tone and promoting bronchodilation

23
Q

Tiotropium: short- or long-acting?

A

Long

24
Q

Tiotropium indications

A

COPD

25
Q

Tiotropium adverse effects

A

Related to anticholinergic effects: dry mouth, throat irritation, blurred vision, dizziness

26
Q

Tiotropium contraindications/risks

A

Risk of angle closure glaucoma

Can worsen/precipitate bladder outlet obstruction

27
Q

Ipratropium class

A

Anticholinergic

28
Q

Ipratropium administration

A

Metered dose inhaler (2 puffs or 42ug 3-4x daily)

29
Q

Ipratropium: short- or long-acting?

A

Short

30
Q

Ipratropium mechanism of action

A

Blocks muscarinic actions of ACh, inhibiting cholinergic bronchomotor tone and promoting bronchodilation

31
Q

Ipratropium indications

A

Symptom relief from asthma/COPD

32
Q

Ipratropium adverse effects

A

Related to anticholinergic effects: dry mouth, throat irritation, blurred vision, dizziness

33
Q

Ipratropium contraindications/risks

A

Risk of angle closure glaucoma

Can worsen/precipitate bladder outlet obstruction

34
Q

Ventolin

A

Salbutamol

35
Q

Seretide

A

Salmeterol/fluticasone

36
Q

Spiriva

A

Tiotropium

37
Q

Atrovent

A

Ipratropium

38
Q

Bricanyl

A

Terbutaline

MD2 Pharmacology (6 decks)

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