respiratory Flashcards
hypoplasia
def
what it leads to
congenital abnormality
1. any condition which impedes the development of the thoracic cavity 2. may lead to unilateral or bilateral underdevelopment of the lungs.
diaphragmal hernia
congenital abnormality
partial or total absence of the diaphragm may result in herniation of the abdominal contents into the thoracic cavit
respiratory tract congenital abnormalities (4)
- hypoplasia
- diaphragmal hernia
- bronchogenic cysts
- bronchopulmonary sequestration
bronchogenic cysts
peribronchial cysts lined by bronchial epithelium which cause abcesses or themselves will rupture (congenital abnormality)
Bronchopulmonary sequestration
what it is
where it can occur
- lung tissue that has no connection with the bronchial system.
- It may occur in an extralobar (outside the visceral pleura) or intralobar (within the visceral pleura) location.
atelectasis
def
primary
secondary
- refers to a condition of incomplete expansion of alveoli
- primary - results from the failure of lungs to ventilate at the time of birth due (premature babies)
- secondary - may be due to deficiency of surfactant
bronchiectasis
def
results from (2)
symptoms (2)
- permanent dilatation of bronchi and bronchioles due to destruction of the muscle and elastic supporting tissue
- resulting from chronic necrotizing infections, or mechanical obstruction of bronchi (eg tumors)
- symptoms: cough and expectoration of purulent sputum.
viral pneumonia
what it is
exudate?
symptom
- peribronchiolar lesions that are within the alveolar walls and are widened by edema
- alveolar spaces are free of exudate.
- symptom- persistent non-productive cough
bacterial pneumonia def 2 classifications
- inflammation and solidification of pulmonary parenchyma
classified as: - bronchopneumonia: consolidation w/patchy distribution (usually lower lobe)
- lobar pneumonia: extensive consolidation involving entire lobe usually due to streptococcus pneumoniae
pneumococcal pneumonia development (4)
- congestion: bacterial proliferation and inflammatory response & serous exudation into alveolar space
- red hepatization: outpouring of neutrophils and precipitated fibrin into alveolar space
- gray hepatization: disintegration of neurto-phils and erythrocytes with accumulation of fibrin
- resolution: digestion & reabsorption of exudate and restoration of pulmonary parenchyma to normal.
fungal infections (3)
- fungi are week antigens and cause tissue damage primarily by virtue of the hypersensitivity reaction against the fungi proteins
- Most of the deep mycoses (histoplasmosis, coccidoidomycosis, blastomycosis etc.) produce chronic granulomatous disease.
- Candida and Aspergilus infections occurring as an opportunistic in AIDS or after antibiotic or cytotoxic therapy.
lung abscess
biology
results from
- localized suppuration and liquefaction necrosis of lung parenchyma
- resulting from aspiration of foreign material usually due to altered consciousness (alcoholism, drug overdose, epilepsy etc..)
restrictive vs. obstructive disease
- restrictive- reduced expansion of lunch parenchyma => decreased total lung capacity
- obstructive- resistance to air flow => expiratory flow rate is decreased
examples of ORD (4)
- asthma
- emphysema
- chronic bronchitis
- bronchiectasis
asthma
what its caused by
manifestations (3)
- episodic, reversible bronchoconstriction
2. manifested by dyspena, cough and wheexing