Respiratory Flashcards
What should do if think its asthma and QoL is affected?
QoL affected confirm diagnosis with a trial of ICS
QoL not affected, watch and see
What is asthma?
Chronic
Wheeze, Cough, SOB
Multiple triggers-although in children the predominant trigger is an URTI
Variable/reverisble
RESPONDS TO ASTHMA TX
Is asthma a diagnosis of exclusion?
NOOOOO
Key words:
- Wheeze
- Variability
- Respond to treatment
What causes asthma?
- Host response to environment
- Infection
- Physiology abnormal before symptoms
- It is a syndrome
- Genetics (ADAM33, ORMDL3 (not all people with these genes have asthma))- interact with environment
What are some asthma syndromes (multiple hits)?
All go into a final common pathway
- Infant onset
- Childhood onset
- Adult onset
- Exertional asthma
- Occupational asthma
Does allergy cause asthma?
Thats a nope (not directly related)
Primary epithelial (skin, airway, gut) abnormality results in:
1) Eczema/asthma etc
2) Allergy
Allergy then fuels (sensitisation) eczema/asthma etc
Early environment causes childhood asthma: what are some of these interventions to change environments to reduce exposure?
- Feeding (breast, late weaning
- Allergen (ante- and post natal)
- Smoking
Is there a diagnostic test for asthma in children?
NO
Tests can be useful (excluding>diagnosing)
What makes spirometery useful?
Bronchodilator response to measure the lung function
Asthma diagnosis tests (more for exclusion of other things?
- Spirometry
- BDR
- FeNO
- Peak flow
Asthma diagnosis tests (more for exclusion of other things?
- Spirometry
- BDR
- FeNO
- Peak flow
Why is it hard to diagnose asthma in <5s?
Uncertainty greatest in <5s
Tests not reliable in <5s
Tests not great anyway
Does a cough variant asthma exist in children?
NOOOOOO
Rattle of … & the whistle of …
Rattle of bronchitis and the whistle of asthma
Do you get a Hx of SOB in asthma?
YES DUH
- Sig resp difficult (<30% lung function)
- Airway obstruction
- ‘Sooking’ in of ribs with wheeze
What kind of cough is associated with asthma?
- Dry
- Nocturnal (just after falling asleep)
- Exertional
What is the treatment/diagnosis of asthma?
ICS for 2 months
Remember false positive responses-inhaler holiday
What Hx do you ideally need to diagnose asthma (hindsight diagnosis)
Wheeze (with & w/o URTI)
SOB @ rest
Parental asthma
Responds to Tx
What are the harms of a trial of treatment for asthma and what are the benefits?
Harm=0.5-1cm loss in height, oral thrush
Benefit=helps diagnosis and if symptoms respond it improves QoL & reduces risk of attacks
What are the harms of a trial of treatment for asthma and what are the benefits?
Harm=0.5-1cm loss in height, oral thrush
Benefit=helps diagnosis and if symptoms respond it improves QoL & reduces risk of attacks
Under 18 months respiratory symptoms are most likely infection and >5 most likely asthma but…?
If it sounds like asthma & responds to asthma Tx it is asthma regardless of age!
Are asthma & VIW treated the same?
Yes-they are the same condition
- Preschool children
- Different shades of the same colour
- Should be treated
Is there a cure for asthma?
No, only palliation or spontaneous resolution
How is control measured (what criteria)?
SANE
Short acting beta agonist/week
Absence school/nursery
Nocturnal symptoms/week
Exertional symptoms/week
If patient has been symptom free for 3 months what might you consider in asthma?
Stepping down the treatment
What is the starting treatment for asthma?
Low dose ICS (severe may respond to minimal treatment)
Review after 2 months (inhaler hol-easter)
ICS is the standard preventer so what is SABA?
Blue relieving medication
What is the max dose of ICS in <12 yo?
800microg