Respiration Mechanics Flashcards

1
Q

what is tissue respiration?

A

the aerobic metabolism in cells

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2
Q

what is breathing?

A

gas exchange and the associated processes

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3
Q

what is respiration mechanics?

A

the study of mechanical properties of lung and chest wall and the process by which air enters and leaves the lungs

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4
Q

what is the lungs job?

A

to bring in fresh air rich in oxygen needed to fuel the body and to expel the waste (CO2) produced from cells in the body

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5
Q

why is respiratory mechanics important?

A

to understand how lungs work normally and in disease states, almost all lung disease affect mechanical properties of the lung and death from lung disease is usually due to the inability to overcome changes in lung and/or chest mechanics

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6
Q

what is the resting PO2?

A

100 +/- 2mmHg

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7
Q

what is the resting PCO2?

A

40 +/- 2mmHg

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8
Q

what is the exchange of O2 to CO2 at rest?

A

250ml O2/min and 200ml CO2/min

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9
Q

what is the exchange of O2 and CO2 when breathing regulation is continuous?

A

800ml O2/min and 750ml CO2/min

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10
Q

what is the exchange of CO2 and O2 when you are undertaking severe exercise?

A

5000ml O2/min and 6000ml CO2/min

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11
Q

what is the function of the nasal cavities and paranasal sinuses?

A

filter, warm, humidify air, detect smells

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12
Q

what is the function of the pharynx?

A

conducts air to larynx, a chamber shared with the digestive tract

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13
Q

what is the function of the larynx?

A

protects opening to trachea and contains vocal cords

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14
Q

what is the function of the bronchi and trachea?

A

filters air, traps, particles in mucus and has cartilages to keep airway open

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15
Q

what is the function of the lungs?

A

responsible for air movement through volume changes during movements of ribs and diaphragm; include airways and alveoli

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16
Q

what is the function of the alveoli?

A

act as sites of gas exchange between air and blood

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17
Q

what are the major functions of the upper airway?

A

humidify (saturate with water), warm (to body temp) and filter

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18
Q

what is the epithelium of the upper airways?

A

pseudo-stratified ciliated columnar epithelium

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19
Q

what is the ventilation at rest?

A

about 6L/min, about 12 breaths of 500ml

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20
Q

what is the max ventilation?

A

160L/min, about 40 breaths of 4L

21
Q

what is the cardiac output at rest?

A

5L/min, 70bpm, 70ml/beat

22
Q

what is the max cardiac output?

A

25L/min, 200bpm, 125ml/beat

23
Q

what is inspiration when practising quiet breathing?

A

active

24
Q

explain the mechanism of inspiration in quiet breathing

A

diaphragm contracts downwards pushing abdominal contents outwards, external intercostals pull ribs outwards and upwards

25
Q

what is expiration when practising quiet breathing?

A

passive

26
Q

explain the mechanism of expiration in quiet breathing

A

elastic recoil

27
Q

what is inspiration when practising strenuous breathing?

A

active

28
Q

explain the mechanism of inspiration when strenuous breathing

A

greater contraction of diaphragm (1cm quiet breathing up to 10cm during strenuous breathing) and external intercostals. Inspiratory accessory muscles e.g. sternocleidomastoid, alae nasi and genioglossus

29
Q

what is expiration when practising strenuous breathing?

A

active

30
Q

explain the mechanism of expiration in strenuous breathing

A

abdominal muscles used (rectus abdominus, internal oblique, external oblique and transversus abdominus), internal intercostal muscles oppose external intercostals by pushing ribs down and inwards

31
Q

what is Pa?

A

alveolar pressure

32
Q

why does the Pa = 0 at the beginning of inspiration?

A

because there is no flow

33
Q

what is Ppl?

A

pleural pressure

34
Q

what is Pel?

A

plastic recoil pressure

35
Q

what is Pl?

A

transpulmonary pressure

36
Q

what is Pb?

A

barometric pressure

37
Q

in healthy lungs how efficient is low level breathing?

A

very efficient because there is a small muscle effort

38
Q

in healthy lungs how efficient is higher intensity breathing and why?

A

less efficient because gas flow is more turbulent and it uses more muscles. The accessory muscles can fatigue easily to limit exercise

39
Q

what is the functional residual capacitu?

A

the volume of air in the lung at the end of expiration during quiet breathing

40
Q

what do the elastic recoil forces of the lung do?

A

act to decrease lung volume

41
Q

what does the outward recoil of chest wall do?

A

acts to increase lung volume

42
Q

at functional residual capacity what is the elastic recoil ad the outward recoil like?

A

opposite and equal and muscles are relaxed

43
Q

what happens to the FRC when chest wall muscles are weak?

A

it decreases

44
Q

what is FVC?

A

forces viral capacity

45
Q

what is FEV?

A

forced expiratory volume in 1 second

46
Q

in a healthy individual what is the FEV/FVC ratio and what does this mean?

A

it is greater than 70% meaning that 70% of the lung volume is expired in 1 second

47
Q

in patients with obstructive lung disease what is the FEV/FVC ratio and what does this mean?

A

it is less than 70% meaning that less than 70% of the lung volume is expired in 1 second

48
Q

in patients with restrictive lung disease e.g. pulmonary disease what is the FEV/FVC ratio?

A

greater then 70% because the lung volume (FVC) is smaller