Gas Exchange Flashcards

1
Q

what is the gas concentration gradient in alveoli and capillaries?

A

the gases move down concentration gradients by diffusion and the concentration gradients are the same as pressure gradients

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2
Q

what structures are involved in the conducting airways?

A

bronchi containing cartilage and non respiratory bronchioles

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3
Q

what structures are involved in the respiratory unit?

A

respiratory bronchioles and alveolar ducts

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4
Q

as the airway divides from trachea - bronchioles - alveoli what occurs in each division

A

an increase in number, a decrease in diameter and an increase in surface area

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5
Q

what forms the anatomic dead space?

A

conducting airways (bronchi and non-respiratory bronchioles)

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6
Q

what structures do not take part in gas exchange?

A

conducting airways (bronchi and non-respiratory bronchioles)

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7
Q

what is the approximate volume of the respiratory airways?

A

2500ml

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8
Q

what is the approximate volume of the conducting airways?

A

150ml

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9
Q

what is a respiratory unit?

A

gas exchanging unit, basic physiological unit of the lug consisting of respiratory bronchioles, alveolar ducts and alveoli

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10
Q

what are the type 1 epithelial cells in the alveoli and what do they do?

A

occupy 97% of alveoli and are the primary site of gas exchange

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11
Q

what are the type 2 epithelial cells in the alveoli and what do they do?

A

occupy 3% of the surface area and produce pulmonary surfactant

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12
Q

what does surfactant do?

A

reduce surface tension

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13
Q

what do alveolar macrophages do?

A

removal of debris

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14
Q

what are the characteristics of alveoli which make it perfectly designed for gas exchange ?

A

large surface area, very thin walls, good diffusion characteristics

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15
Q

what is the function of the pulmonary circulation?

A

brings deoxygenated blood from heart to lung and oxygenated blood from lung to heart and then rest of the body

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16
Q

what is the function of the bronchial circulation?

A

brings oxygenated blood to lung parenchyma

17
Q

what does the lymphatic system do?

A

defence and removal of lymph fluid

18
Q

what are the two types of blood circulation in the lungs?

A

pulmonary circulation and bronchial circulation

19
Q

what is the total blood volume in the pulmonary circulation?

A

500ml

20
Q

at rest what is the volume of blood in the alveolar-capillary network?

A

75mls

21
Q

what happens to the volume of blood in the alveolar-capillary network during exercise?

A

increases to 150-200mls due to recruitment of new capillaries secondary to an increase in pressure and flow

22
Q

what is the difference between pulmonary arteries and systemic arteries?

A

pulmonary arteries are thin walled, highly compliant, large diameter and have low resistance

23
Q

what is the distance between the alveoli and a red blood cell

A

1-2upm

24
Q

what lies between an alveoli and a red blood cell?

A

alveolar epithelial cell, capillary endothelial cell and basement membrane

25
Q

in the pulmonary circuit what is the change in O2 and CO2?

A

O2 enters blood and CO2 leaves blood

26
Q

in the systemic circuit what is the change in O2 and CO2?

A

O2 leaves blood and CO2 enters

27
Q

what gradient do gases move down?

A

pressure gradients

28
Q

what is the difference between the O2 and CO2 pressure gradients?

A

the pressure gradient for O2 is much bigger and CO2 is more diffusible

29
Q

describe the pulmonary circulation in terms of volume and pressure

A

carries large volumes of blood at low pressures

30
Q

what exchange happens between the alveoli and the capillary in the pulmonary circulation?

A

CO2 moves from capillary to alveoli and O2 moves from alveoli to capillary