Respi (NP + Patho) Flashcards
list 2 investigation for COPD
- pulmonary function test
- AAT deficiency screening
what is the 2 characteristic of COPD
- chronic bronchitis (inflammation of the bronchial tube, resulting in hypersecretion of mucus in the airway)
- emphysema (alveoli destruction)
which bacteria cause lobar pneumonia + what is the 4 stages
streptococcus pneumonia
day 1-2 (congestion): blood vessels & alveoli start filling w excess fluid
day 3-4 (red hepatization): exudates (containing RBC, neutrophils & fibrins) start filling up the airspace & making them more solid
day 5-6 (grey hepatization): lobe is still solid, but RBC in exudates are broken down (hence grey)
day 8, last for 3 weeks (resolution): exudates are digested by enzymes, ingested by macrophages or cough out
explain how does ventilator pneumonia occur
occur when biofilm (containing protein, sugar & bacteria) form on the surface of endotracheal tube
as patient is already weak and unable to cough, biofilm will move into the lung & cause pneumonia
give 1 example of a virulent and resistant microbes in HAP
methicillin resistant staphylococcus aureus (MRSA)
list 6 risk factor of COPD
- asthma
- alpha1 antitrypsin deficiency
- chemical agents
- > 40 y/o
- smoking
- pollution eg. dust, silica
what is bronchopneumonia
infection of the bronchioles and alveoli
why does pt sit in tripod position + 1 consequence
to promote positive end expiratory pressure (PEEP), however this cause the use of accessory muscle, therefore making the patient more tired
how does chronic hypoxemia leads to cor pulmonale + what is 1 sign of corp pulmonale
it constrict the pulmonary blood vessel resulting in pulmonary HTN
this cause right side of heart to overwork, resulting in right sided HF (cor pulmonale)
1 symptoms: JVD
explain why nosocomial pneumonia are more serious
patient in hospital already have a weakened immune system, furthermore the microbes in hospital are virulent (great offense) and more resistant (great defence) to common atbx, where some of the bacteria are able to swap some of it atbx resistance gene w one another
what is the difference between hypoxemia & hypoxia
hypoxemia - low o2 in blood
hypoxia - low o2 in tissue
what is lobar pneumonia
infection of one/both lobar that results in complete consolidation
what is the most common bacterial cause of community acquired pneumonia
streptococcus pneumoniae
list 3 causes of aspiration pneumonia
- food
- drink
- gastric content (can cause chemical irritation on top of infection)
what is the range of PEFR