Resp Viral/Chlam (lec 10)

Question 1

ARD (Acute Resp Dz) presents?

Answer 1

Infect of up resp mucosa

Snot, cough, ST, malaise

Question 2

ARD agents: Rhinovirus

Season

Carrier

Transmit

Tx

Answer 2

ºcause of ARD

Season: winter

Carrier: human

Transmit: p-to-p/hands, aerosol, fomites

Tx: ～ zinc gluconate OTC

Question 3

ARD agents: Influenza

Types?

Antigenic variations?

Answer 3

A = worst,
B, C

Antigenic Drift: point mutation H or N, minor variation but very important

Antigenic Shift: genome segment exchange (entire H or N), major variation

Question 4

Influenza:

Carrier?

Transmit?

Onset?

Sxs?

Answer 4

Carrier: pigs/chickens

Transmit: resp tract entry

Onset: abrupt

Sxs: fever, ache, chills, cough

Question 5

Influenza:

Mechanism of dz?

Answer 5

destruction of resp tract ciliated epith

Question 6

Influenza:

Complications?

Answer 6

1) ºviral pneumonia, 2º bacterial pneumonia
2) Reyes: kids, a/w asprin+flu
3) GBS

Question 7

Influenza:

Diagnostics?

Tx?

Answer 7

Dx: rapid antigen (naso swab)
*false - early

Tx:
Rimantadine (A) stops uncoating

Tamiflu (A, B) stops release

Question 8

Influenza nomenclature?

Answer 8

Type/Location/Yr isolated/Iso#/Antigen

Question 9

ARD agents: Chlamydiae

Microbe characteristics?

Answer 9

Obligate intracellular parasite
Biochemically restricted (use cell's ATP)

Question 10

Chlamydia trachomatis is?

Passed?

Presents?

Answer 10

STI passed to baby during birth ->
Infant pneumonia
Sxs 3 wks post birth

Rhinitis -> cough

a/w Reiter’s in adults

Question 11

Chlamydophila pneumoniae causes?

a/w?

Answer 11

bronchitis
pneumo
sinusitis

a/w atherosclerosis