Resp System Histology Flashcards

1
Q

resp system functions

A

supply O2 to blood for delivery to cells throughout body

remove CO2 that has been accumulated in the blood from tissues of body

phonation

olfaction

lung function in B.P. control via renin-angiotension system

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2
Q

air to lungs

A

series of conducting pathways

air enters nose/mouse - pharnynx + larynx - trachea - principal bronchi -
lungs - bronchus - smaller bronchi - bronchiles - alveolar sacs

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3
Q

where does gas exchange occur

A

alveolar sacs

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4
Q

nasal cavity roles

A

warming
moistening
filtering inspired air

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5
Q

what does the root of the nasal cavity contain

A

olfactory epithelium

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6
Q

epithelial lining

A

vestibule - keratinised stratified squamous epithelium
deeper - keratin = lost
deeper again = epithelium

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7
Q

what lies under resp epithelium

A

lamina propia

band of loose connective tissue containing seromucous glands + thin walled venous sinuses

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8
Q

thin walled venous sinuses can

A

quickly engorge with blood + block nose

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9
Q

what is lined by non-keratinized stratified squamous epithelium and why

A

oropharynx, anterior surface + upper part of posterior surface of epiglottis

oropharynx transmits both air + food

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10
Q

walls of larynx make up

A

cartilage + muscles

resp epithelium lining its surface

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11
Q

vocal cords + adjacent structures are covered with what

A

stratified squamous epithelium

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12
Q

trachea is continuous with what

A

larynx

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13
Q

trachea contains how many cartilages

A

15-20 C shaped cartialages

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14
Q

opening of C shaped cartilage spanned by

A

fibroelastic tissue + smooth muscle

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15
Q

trachea lining

A
respiratory epithelium
basal lamina
lamina propria
submucosa
seromuccous glands
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16
Q

trachea divides into

A

2 main bronchi

17
Q

walls of bronchus made up od

A

resp epithelium
lamina propia
muscularis
= ring of smooth muscle + submucossa + adipose tissue + seromuccous glands

18
Q

bronchial tree

A

bronchi branch = smaller cartillage = more discontinuous = airway 1mm in diameter = bronchioles

19
Q

bronchioles

A

less than 1mm in diameter
lack cartilage
few goblet cells

20
Q

what is the lamina propria composed of

A

smooth muscle + elastic + collagen fibres

21
Q

terminal bronchioles

A

smallest bronchioles

lack resp function

22
Q

smooth muscle of bronchioles

A

respond to parasympathetic innervation
histamine
other factors

contracting + constricting bronchiole diameter

23
Q

smooth muscle of bronchioles plays a key role in what

A

asthma

allergic reaction

24
Q

terminal bronchioles are lined with

A

cuboidal ciliated epitheliu

25
Q

what do terminal bronchioles contain

A

non-ciliated club cells

26
Q

roles of club cells

A

stem cells
detoxification
immune modulation
surfactant production

27
Q

what interrupts continuity of resp bronchioles

A

alveoli

28
Q

conducting bronchioles

A

trachea - terminal bronchioles

no exchange of O2/CO2 with blood

29
Q

gas exchange occurs where

A

alveoli (honeycomb shape)

30
Q

alveoli are lined by

A

type 1 alveolar cells

type 2 alveolar cells

31
Q

type 1 alveolar cells

A

simple squamous epithelium
line alveolar surfaces
barrier of minimal thickness
permeable to gases

32
Q

type 2 alveolar cells

A

lamellar bodies contain surfactant
surfactant - spreads over pulmonary surface - reduce surface tension + air fluid interface
reduces - tendency for alveoli to collapse - end of expiration

33
Q

alveolar macrophages

A

free cells in septa or migrating over luminal surfaces

34
Q

septa between alveoli

A

permeated by capillary networks

35
Q

air-blood barrier

A

thin tissue

type 1 cell

36
Q

visceral pleur

A

multi-layered
outer layer = mesothelium = simple squamous epithelium

backed by = layers of fibrous + elastic connective tissue

between = pleural cavity = small amount of lubricating fluid