Resp Pharmacology Flashcards

1
Q

Theophylline MOA? AE?

A

MOA: inhibits phosphodiesterase=>increased cAMP and bronchodilation

AE: inhibits adenosine, ventricular arrhythmia/tachycardia

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2
Q

Ipratropium MOA? DOC for? Long Form?

A

MOA: competitively blocks muscarinic receptors=> preventing bronchoconstriction

DOC: Bronchospasm caused by B-Blockers
Long Form: Tiotropium

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3
Q

Cromolyn MOA? Use? AE?

A

MOA: prevents degranulation of mast cells
Use: seasonal allergies
AE: throat irritation

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4
Q

Fluticasone/budesonide MOA? 1st line for? AE?

A

MOA: 1. Inhibit all cytokine 2. Inhibit NF-kB (the transcription factor that induces TNF-alpha)

DOC: Chronic Asthma

AE? oral candidiasis

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5
Q

Dextromethorphan MOA? Antidote?

A

MOA: blocks NMDA glutamate receptors
Antidote: Naloxone

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