Resp Pharmacology Flashcards
Theophylline MOA? AE?
MOA: inhibits phosphodiesterase=>increased cAMP and bronchodilation
AE: inhibits adenosine, ventricular arrhythmia/tachycardia
Ipratropium MOA? DOC for? Long Form?
MOA: competitively blocks muscarinic receptors=> preventing bronchoconstriction
DOC: Bronchospasm caused by B-Blockers
Long Form: Tiotropium
Cromolyn MOA? Use? AE?
MOA: prevents degranulation of mast cells
Use: seasonal allergies
AE: throat irritation
Fluticasone/budesonide MOA? 1st line for? AE?
MOA: 1. Inhibit all cytokine 2. Inhibit NF-kB (the transcription factor that induces TNF-alpha)
DOC: Chronic Asthma
AE? oral candidiasis
Dextromethorphan MOA? Antidote?
MOA: blocks NMDA glutamate receptors
Antidote: Naloxone