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Pharmacology > Adverse Effects > Flashcards

Adverse Effects Flashcards

1
Q

Coronary vasospasm

A

Cocaine, sumatriptan, ergot alkaloids

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2
Q

Cutaneous flushing

A

Vancomycin, Adenosine, Niacin, Ca2+ channel
blockers
VANC

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3
Q

Dilated

cardiomyopathy

A

Doxorubicin, daunorubicin

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4
Q

Torsades de pointes

A

Class III (e.g., sotalol) and class IA (e.g.,
quinidine) antiarrhythmics, macrolide
antibiotics, antipsychotics, TCAs

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5
Q

Adrenocortical

insufficiency

A

HPA suppression 2° to glucocorticoid

withdrawal

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6
Q

Hot flashes

A

Tamoxifen, clomiphene

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7
Q

Hyperglycemia

A

Tacrolimus, Protease inhibitors, Niacin, HCTZ,
b-blockers, Corticosteroids
Taking Pills Necessitates Having Blood
Checked

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8
Q

Hypothyroidism

A

Lithium, amiodarone, sulfonamides

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9
Q

Acute cholestatic

hepatitis, jaundice

A

Erythromycin

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10
Q

Diarrhea

A

Metformin, Erythromycin, Colchicine, Orlistat,
Acarbose
Might Excite Colon On Accident

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11
Q

Focal to massive

hepatic necrosis

A

Halothane, Amanita phalloides (death cap
mushroom), Valproic acid, Acetaminophen
Liver “HAVAc”

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12
Q

Hepatitis

A

INH

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13
Q

Pancreatitis

A

Didanosine, Corticosteroids, Alcohol, Valproic acid,
Azathioprine, Diuretics (furosemide, HCTZ)
Drugs Causing A Violent Abdominal Distress

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14
Q

Pseudomembranous

colitis

A

Clindamycin, ampicillin, cephalosporins Antibiotics predispose to superinfection by
resistant C. difficile

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15
Q

Agranulocytosis

A

Dapsone, Clozapine, Carbamazepine,
Colchicine, Methimazole, Propylthiouracil
Drugs CCCrush Myeloblasts and
Promyelocytes

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16
Q

Aplastic anemia

A

Carbamazepine, Methimazole, NSAIDs,
Benzene, Chloramphenicol, Propylthiouracil
Can’t Make New Blood Cells Properly

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17
Q

Direct Coombspositive
hemolytic
anemia

A

Methyldopa, penicillin

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18
Q

Gray baby syndrome

A

Chloramphenicol

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19
Q

Hemolysis in G6PD

deficiency

A

INH, Sulfonamides, Dapsone, Primaquine,
Aspirin, Ibuprofen, Nitrofurantoin
Hemolysis IS D PAIN

20
Q

Megaloblastic anemia

A

Phenytoin, Methotrexate, Sulfa drugs Having a blast with PMS

21
Q

Thrombocytopenia

A

Heparin, cimetidine

22
Q

Thrombotic

complications

A

OCPs (e.g., estrogens)

23
Q

Fat redistribution

A

Protease inhibitors, Glucocorticoids Fat PiG

24
Q

Gingival hyperplasia

A

Phenytoin, verapamil, cyclosporine, nifedipine

25
Q

Hyperuricemia (gout)

A

Pyrazinamide, Thiazides, Furosemide, Niacin,
Cyclosporine
Painful Tophi and Feet Need Care

26
Q

Myopathy

A

Fibrates, niacin, colchicine,
hydroxychloroquine, interferon-α,
penicillamine, statins, glucocorticoids

27
Q

Osteoporosis

A

Corticosteroids, heparin

28
Q

Photosensitivity

A

Sulfonamides, Amiodarone, Tetracyclines,
5-FU
SAT For Photo

29
Q

Rash (Stevens-

Johnson syndrome)

A

Anti-epileptic drugs (ethosuximide,
carbamazepine, lamotrigine, phenytoin,
phenobarbital), Allopurinol, Sulfa drugs,
Penicillin
Steven Johnson has epileptic Allergy to Sulfa
drugs and Penicillin

30
Q

SLE-like syndrome

A

Sulfa drugs, Hydralazine, INH, Procainamide,
Phenytoin, Etanercept
Having lupus is “SHIPP-E”

31
Q

Teeth discoloration

A

Tetracyclines

32
Q

Tendonitis, tendon
rupture, and cartilage
damag

A

Fluoroquinolones

33
Q

Cinchonism

A

Quinidine, quinine

34
Q

Parkinson-like

syndrome

A

Antipsychotics, Reserpine, Metoclopramide Cogwheel rigidity of AR

35
Q

Seizures

A

INH (vitamin B6 deficiency), Bupropion,
Imipenem/cilastatin, Tramadol, Enflurane,
Metoclopramide
With seizures, I BITE My tongue

36
Q

Tardive dyskinesia

A

Antipsychotics, metoclopramide

37
Q

Diabetes insipidus

A

Lithium, demeclocycline

38
Q

Fanconi syndrome

A

Expired tetracycline

39
Q

Hemorrhagic cystitis

A

Cyclophosphamide, ifosfamide Prevent by coadministering with mesna

40
Q

Interstitial nephritis

A

Methicillin, NSAIDs, furosemide

41
Q

SIADH

A

Carbamazepine, Cyclophosphamide, SSRIs Can’t Concentrate Serum Sodium

42
Q

Dry cough

A

ACE inhibitors

43
Q

Pulmonary fibrosis

A

Bleomycin, Amiodarone, Busulfan,
Methotrexate
Breathing Air Badly from Medications

44
Q

Antimuscarinic

A

Atropine, TCAs, H1-blockers, antipsychotics

45
Q

Disulfiram-like

reaction

A

Metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st-generation sulfonylureas

46
Q

Nephrotoxicity/

ototoxicity

A

Aminoglycosides, vancomycin, loop diuretics, cisplatin

Pharmacology (8 decks)

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