Research methods in neuroscience Flashcards

1
Q

Is a CT scan invasive or non-invasive?

A

Non-invasive

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2
Q

What is a CT scan?

A

An x-ray scanner that is rotated 1 degree at a time of 180degrees. Reveals structural abnormalities, such as a lesion. It is computer assisted.

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3
Q

Is an MRI scan invasive or non invasive?

A

Non-invasive

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4
Q

What is an MRI scanner?

A

Contains a strong magnetic field that that causes protons to align in the same orientation. A computer reconstructs the image. The MRI scanner detects radiation emitted as the protons relax.

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5
Q

Is an fMRI invasive or non-invasive?

A

Non-invasive

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6
Q

What does the fMRI measure?

A

Which parts of the brain are active when performing a task. Where functional activity occurs

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7
Q

How come you can see the brain activity with an fMRI?

A

As oxygen and glucose are supplied by the blood as fuel for the brain but the brain does not store fuel so blood supply changes as needs arise

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8
Q

Is an EEG invasive or non-invasive?

A

Non-invasive

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9
Q

What does an EEG do?

A

Measures the electrical activity of the brain often in response to a stimulus

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10
Q

What is some good advantages about the EEG?

A

High temporal resolutions
Direct reflection of neuronal activity
Less expensive than MRI

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11
Q

What is a negative of the EEG

A

Poor spatial localisation due to recordings made at the scalp

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12
Q

What does ERP stand for?

A

Event related potentials

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13
Q

Are ERPs invasive or non-invasive?

A

Non-invasive

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14
Q

What do ERP waveforms tell us about?

A

The neural basis of processing which is provided by the difference in activity.

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15
Q

What are the two invasive methods?

A

Intracellular recording and extracellular recording

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16
Q

What are the two stimulation techniques?

A

Electrical and optogenetic

17
Q

What is optogenetic stimulation

A

Changing the brain in a way that make the neurons very sensitive to light

18
Q

What are the two paradigms to measure species-common behaviours?

A

The open field test and social defeat

19
Q

What does the open field test involve?

A

A chamber to allow the animal to move around

20
Q

What does the social defeat assessment involve?

A

An unfamiliar individual (INTRUDER) introduced to the habitat of a larger or more aggressive individual (RESIDENT).

21
Q

What are the three conditioning paradigms?

A

Classical conditioning, place preference, operant conditioning

22
Q

Describe place preference

A

For drug addiction
Day 1 - assess natural preference
Day 2-4 - AM saline PM drug
Day 5 - assess conditioned performance

23
Q

What is operant conditioning associated with?

A

Rewards and punishment

24
Q

What is classical conditioning associated with?

A

Stimulus response links

25
Q

What do learning paradigms aim to do?

A

Teach the animal to associate one stimulus with another or one response with an outcome

26
Q

What do field observations usually focus on?

A

Species common behaviours