Reproductive Pathology Flashcards
1
Q
What are the characteristics of Seminoma Testicular Tumors?
- Presentation
- Histology
- Frequency
A
- Malignant
- Painless mass
- Most common tumor overall
- Fried egg appearance of cells
2
Q
What are the characteristics of Embryonal CA of the testes?
- Presentation
- Histology
- Lab values
A
- Malignant
- Painful mass
- Glandular/papillary morphology
- Normal AFP but elevated hCG
3
Q
What are the characteristics of Yolk Sac Testicular Tumors?
- Population
- Histology
- Lab values
A
- Most common up to age 3
- Schiller-Duval Bodies
- Increased AFP
4
Q
What are the characteristics of Choriocarcinoma of the testes?
- Histology
- Lab values
- Metastasis
A
- Malignant
- Syncytiotrophoblasts and cytogrophoblasts
- Increased hCG
- Hematogenous mets to lungs and brain
5
Q
What are the characteristics of Testicular Teratomas?
- Appearance
- Lab values
- Difference from female teratoma
A
- Teeth and Hair may be present
- Increased hCG and/or AFP
- May be malignant
- not in females
6
Q
What are the characteristics of Leydig Cell Tumors?
- Appearance
- Histology
- Lab values
- Signs/Symptoms
A
- Gold-brown color
- Reinke crystals
- Androgen producing
- Gynecomastia in men
- Precocious puberty in boys
7
Q
What are the characteristics of Sertoli Cell Tumors?
- Lab values
- Signs/symptoms
A
- Secrete Estrogens
- Gynecomastia
8
Q
What are the characteristics of Testicular Lymphoma?
- Population affected
- Origin
A
- Most common in older men
- (not a primary cancer, it is a lymphoma)