Reproductive Pathology Flashcards

1
Q

What are the characteristics of Seminoma Testicular Tumors?

  • Presentation
  • Histology
  • Frequency
A
  • Malignant
  • Painless mass
  • Most common tumor overall
  • Fried egg appearance of cells
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2
Q

What are the characteristics of Embryonal CA of the testes?

  • Presentation
  • Histology
  • Lab values
A
  • Malignant
  • Painful mass
  • Glandular/papillary morphology
  • Normal AFP but elevated hCG
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3
Q

What are the characteristics of Yolk Sac Testicular Tumors?

  • Population
  • Histology
  • Lab values
A
  • Most common up to age 3
  • Schiller-Duval Bodies
  • Increased AFP
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4
Q

What are the characteristics of Choriocarcinoma of the testes?

  • Histology
  • Lab values
  • Metastasis
A
  • Malignant
  • Syncytiotrophoblasts and cytogrophoblasts
  • Increased hCG
  • Hematogenous mets to lungs and brain
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5
Q

What are the characteristics of Testicular Teratomas?

  • Appearance
  • Lab values
  • Difference from female teratoma
A
  • Teeth and Hair may be present
  • Increased hCG and/or AFP
  • May be malignant
    • not in females
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6
Q

What are the characteristics of Leydig Cell Tumors?

  • Appearance
  • Histology
  • Lab values
  • Signs/Symptoms
A
  • Gold-brown color
  • Reinke crystals
  • Androgen producing
    • Gynecomastia in men
    • Precocious puberty in boys
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7
Q

What are the characteristics of Sertoli Cell Tumors?

  • Lab values
  • Signs/symptoms
A
  • Secrete Estrogens
    • Gynecomastia
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8
Q

What are the characteristics of Testicular Lymphoma?

  • Population affected
  • Origin
A
  • Most common in older men
  • (not a primary cancer, it is a lymphoma)
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