Autoantibodies Flashcards

1
Q

Anti-IgG Ab

A

aka Rheumatoid Factor

RA

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2
Q

Anti-Citrullinated Protein Ab (ACPA)

A

RA

(more specific than Rheumatoid factor)

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3
Q

Antinuclear Ab (ANA)

A

SLE

non-specific, screening test

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4
Q

Anti-Smith Ab

A

SLE

More specific

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5
Q

Anti-dsDNA Ab

A

Lupus Renal Disease

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6
Q

Anti-histone Ab

A

Drug-induced Lupus

  • “SHIPP”
    • Sulfonamides
    • Hydralazine
    • Isoniazid
    • Procainamide
    • Phenytoin
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7
Q

Anti-centromere Ab

A

CREST Scleroderma

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8
Q

Anti-Scl-70

A

(aka Anti-Topoisomerase II Ab)

Diffuse Scleroderma

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9
Q

Anti-Jo-1 Ab

A

Polymyositis

Dermatomyositis

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10
Q

Anti-SSA Ab

A

(aka Anti-Ro Ab)

Sjogren Syndrome

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11
Q

Anti-SSB Ab

A

(aka anti-La Ab)

Sjogren Syndrome

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12
Q

Anti-U1-RNP Ab

A

Mixed Connective Tissue Disease

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13
Q

Anti-desmoglein Ab

A

Pemphigus Vulgaris

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14
Q

Anti-ACh Receptor Ab

A

Myasthenia Gravis

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15
Q

Anti-endomysial Ab

A

Celiac

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16
Q

Anti-tissue transglutaminase Ab

A

Celiac

17
Q

Anti-gliadin Ab

A

Celiac

18
Q

Anti-mitochondrial Ab

A

Primary Biliary Cirrhosis

19
Q

Anti-smooth muscle Ab

A

Autoimmune Hepatitis

20
Q

Anti-glutamate decarboxylase Ab

A

Type 1 Diabetes Mellitus

21
Q

Anti-thyrotropin receptor Ab

A

Graves

22
Q

Anti-Thyroid peroxidase Ab

A

(anti-TPO)

Hashimoto’s

23
Q

Anti-Thyroglobulin Ab

A

Graves

Hashimoto’s

24
Q

Anti-basement membrane Ab

A

Goodpasture Syndrome

25
Q

c-ANCA

A

Granulomatosis with Polyangiitis

(aka Wegener’s Granulomatosis)

26
Q

p-ANCA

A

Pauci-immune Crescenteric GN

Churg-Strauss

Microscopic Polyangiitis