Autoantibodies Flashcards
1
Q
Anti-IgG Ab
A
aka Rheumatoid Factor
RA
2
Q
Anti-Citrullinated Protein Ab (ACPA)
A
RA
(more specific than Rheumatoid factor)
3
Q
Antinuclear Ab (ANA)
A
SLE
non-specific, screening test
4
Q
Anti-Smith Ab
A
SLE
More specific
5
Q
Anti-dsDNA Ab
A
Lupus Renal Disease
6
Q
Anti-histone Ab
A
Drug-induced Lupus
- “SHIPP”
- Sulfonamides
- Hydralazine
- Isoniazid
- Procainamide
- Phenytoin
7
Q
Anti-centromere Ab
A
CREST Scleroderma
8
Q
Anti-Scl-70
A
(aka Anti-Topoisomerase II Ab)
Diffuse Scleroderma
9
Q
Anti-Jo-1 Ab
A
Polymyositis
Dermatomyositis
10
Q
Anti-SSA Ab
A
(aka Anti-Ro Ab)
Sjogren Syndrome
11
Q
Anti-SSB Ab
A
(aka anti-La Ab)
Sjogren Syndrome
12
Q
Anti-U1-RNP Ab
A
Mixed Connective Tissue Disease
13
Q
Anti-desmoglein Ab
A
Pemphigus Vulgaris
14
Q
Anti-ACh Receptor Ab
A
Myasthenia Gravis
15
Q
Anti-endomysial Ab
A
Celiac