Reproductive Hormones Flashcards

1
Q

GnRH meaning

A

Gonadotropin Releasing Hormone

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2
Q

Source of GnRH

A

Hypothalamic surge and tonic centers

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3
Q

Female and Male Primary Action of GnRH

A

Release of FSH and LH from anterior lobe-pituitary

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4
Q

Source of LH

A

Anterior lobe (pituitary) gonadotroph cells

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5
Q

Male Primary Action of LH

A

Stimulates testosterone production

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6
Q

Female Primary Action of LH

A

Stimulates ovulation, formation of CL and progesterone secretion

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7
Q

Source of FSH

A

Anterior lobe (pituitary) gonadotroph cells

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8
Q

Male Primary Action of FSH

A

Sertoli cell function

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9
Q

Female Primary Action of FSH

A

Follicular development and estradiol synthesis

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10
Q

Source of Prolactin

A

Anterior lobe (pituitary) lactotroph cells

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11
Q

Male Primary Action of Prolactin

A

Can induce maternal behavior

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12
Q

Female Primary Action of Prolactin

A

Lactation, maternal behavior and corpora lutea function

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13
Q

Sourced of Oxytocin (OT)

A

Synthesized in the hypothalamus, stored in the posterior-lobe pituitary, synthesized by corpus luteum

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14
Q

Male Primary Action of Oxytocin

A

PGF2a synthesis and pre-ejaculatory movement of spermatozoa

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15
Q

Female Primary Action of Oxytocin

A

Uterine motility, promotes uterine PGF2a synthesis, milk ejection

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16
Q

Source of Estradiol (E2)

A

Granulosal cells of follicle, placenta, Sertoli cells of testis

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17
Q

Male Primary Action of E2

A

Sexual behavior

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18
Q

Female Primary Action of E2

A

Sexual behavior, GnRH, elevated secretory activity of entire tract, enhanced uterine motility

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19
Q

Source of Progesterone

A

Corpus luteum and placenta

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20
Q

Female Primary Action of P4

A

Endometrial secretion, inhibits GNRH release, inhibits reproductive behavior, promotes maintenance of pregnancy

21
Q

Source of Testosterone

A

Interstitial cells of Leydig, cells of theca interna in female

22
Q

Male Primary Action of Testosterone

A

Anabolic growth, promotes spermatogenesis, promotes secretion of accessory sex glands

23
Q

Female Primary Action of Testosterone

A

Substrate for E2 synthesis, abnormal masculinization (hair patterns, voice, behavior, etc)

24
Q

Source of Inhibin

A

Granulosa cells (female)

Sertoli cells (male)

25
Q

Male and Female Primary Action of Inhibin

A

Inhibits FSH secretion

26
Q

Source of Activin

A

Granulosal cells (female)

Sertoli cells (male)

Placental cells (female humans)

27
Q

Male and Female Primary Action of Activin

A

Stimulates FSH secretion

28
Q

Source of Prostaglandin F2a

A

Uterine endometrium, vesicular glands

29
Q

Male Primary Action of PGF2a

A

Affects metabolic activity of spermatozoa, causes epididymal contractions

30
Q

Female Primary Action of PGF2a

A

Luteolysis, promotes uterine tone and contraction, ovulation

31
Q

Source of Prostaglandin E2

A

Ovary, Uterus, Embryonic membranes

32
Q

Female Primary Action of PGE2

A

Ovulation, stimulates corpus luteum secretion of progesterone

33
Q

Source of human chorionic gonadotropin (hcG)

A

Trophoblast of blastocyst (chorion)

34
Q

Male Primary Action of hCG

A

Increase growth of fetal testis

35
Q

Female Primary Action of hCG

A

Facilitate production of progesterone by ovary

36
Q

Source of Equine chorionic gonadotropin (eCG)

A

Chorionic girdle cells

37
Q

Female Primary Action of of eCG

A

Causes formation of accessory corpora lutea

38
Q

Source of placental lactogen

39
Q

Female Primary Action of Placental lactogen

A

Mammary stimulation of dam

40
Q

It is from CL, uterus, and placenta; at the end of pregnancy it stimulate opening of cervix, relaxation of pelvic ligaments, and separation of pelvic symphysis (parturition)

41
Q

It is less abundant and less effective than testosterone, made by Leydig cells

A

Androstenone

42
Q

(I) Follicular Phase, what is the pituitary hormone effect?

A

LH and FSH stimulate several follicles to grow

43
Q

(II) Ovulation, what is the pituitary hormone effect?

A

LH and FSH stimulate maturation of one of the growing follicles

44
Q

(III) Luteal Phase, what is the pituitary hormone effect?

A

LH stimulates growth of a CL from follicular tissue left behind after ovulation

45
Q

In males, what is the pituitary hormone effect?

A

LH and FSH stimulate spermatogenesis and testosterone secretion by the testes

46
Q

In males, what is the testosterone hormone effect?

A

Testosterone and inhibin inhibit the secretion of GnRH by the hypothalamus and LH and FSH by the pituitary

47
Q

HPG means?

A

Hypothalamus-Pituitary-Gonadal Axis

48
Q

FSH and LH levels are elevated

49
Q

E2 and T4 activate HPG axis that will result to physiological changes

A

At puberty