Reproductive Disorders: Male Flashcards

1
Q

When you have acquired hypogonadism, the testes become _______________.

A

small and soft (“like your cheek”)

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2
Q

What metabolic liver disorder can cause testicular atrophy?

A

Hemachromatosis, because iron deposits selectively in gonadotrophs –presents with low FSH/LH and low T

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3
Q

It’s thought that ______________ may account for the decrease in total testosterone in older men.

A

decreased sex-hormone-binding globulin

Note: this would result in the same level of free (physiologically active) testosterone. This is why some people think the total testosterone test is inaccurate.

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4
Q

Hypergonadotrophic hypogonadism usually presents with elevated ________________.

A

FSH and LH, with FSH usually being higher than LH

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5
Q

True or false: high levels of FSH and LH indicate testicular causes of hypogonadism.

A

True, but there can be cases in which pituitary tumors secrete high levels of LH and FSH and the testicles get exhausted.

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6
Q

One study showed that _____________ could increase levels of SHBG and total testosterone.

A

weight loss

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7
Q

Testosterone therapy has been shown to increase risk of _______________.

A

cardiac events, including death; the risk correlated with higher initial testosterone

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8
Q

If __________ happens in a man being treated with testosterone, then he must see a urologist.

A

PSA increases by more than 1.5 ng/ml in 12 months

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9
Q

There are two forms of inhibin. Which is the influential one?

A

Inhibin B

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10
Q

What happens to Leydig cells and Sertoli cells in Klinefelter’s?

A

There are no Sertoli cells. Leydig cells remain, but they are dysfunctional.

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11
Q

Which gonadotrophic hormone will be higher in those with Klinefelter’s?

A

FSH because they have no Sertoli cells and thus cannot make inhibin B

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