Reproductive and Sexual Health Flashcards
What happens to Wollfian and Mullerian ducts in females?
Wollfian degenerates
Mullerian - reproductive tract
What happened to wollfian and mullerian ducts in males?
Mullerian degenerates
Wollfian - male genital tract
What hormones are involved in the development of male genital tract in males and are absent in females?
Testosterone
Mullerian inhibiting factor
What hormone stimulates male external genital formation?
Dihydrotestosterone
What is testosterone converted to?
Dihydrotestosterone
What is the name for undescended testes?
Cryptorchidism
Where is testosterone produced?
Leydig cells
Where are the spermatogenic cells located?
Seminferous tubule
What route does sperm take?
Testes - epididymis - vas deferens - ejaculatory duct - urethra
Name 3 causes of male infertility?
Low sperm count Obstructive - congential, cf Non obstructive - klinefelters, chemotherapy Endocrine Erectile difficulties
What is the indiction for intra-uterine insemination?
Low sperm count
What is the indication for surgical sperm aspiration?
Azoospermia
What is the indication for intracytoplasmic sperm injection?
Very low sperm count
What are the indications for donor sperm insemination?
Azoospermia, low sperm count, genetic conditions
What is the target for the HIV virus?
CD4+ receptors
Why does HIV cause susceptibility to infection?
Causes a reduction in proliferation and circulation of CD4 cells and a reduction in CD8 T cell activation
What is the normal range for CD4 cells?
500-1600cells/mm cubed
At what CD4 count is the risk of opportunistic infections highest?
Less than 200cm
When is a HIV primary infection likely to present and what are the symptoms?
2-4 weeks after infection
Fever, rash, myalgia, pharyngitis, headache
Name the 4 likely opportunistic infections in HIV?
And at what CD4 counts do they present?
Pneumocystis pneumonia - less than 200
TB
Cerebral toxoplasmosis - less than 150
Cytomegalovirus - less than 50
What organism causes pneumocystis pneumonia?
Pneumocystis jiroveci
What virus causes kaposi’s sarcoma?
Human herpes virus 8
What is the risk a baby of HIV infected mother will also become infected?
1 in 4