Reproductive and Sexual Health Flashcards

1
Q

What happens to Wollfian and Mullerian ducts in females?

A

Wollfian degenerates

Mullerian - reproductive tract

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2
Q

What happened to wollfian and mullerian ducts in males?

A

Mullerian degenerates

Wollfian - male genital tract

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3
Q

What hormones are involved in the development of male genital tract in males and are absent in females?

A

Testosterone

Mullerian inhibiting factor

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4
Q

What hormone stimulates male external genital formation?

A

Dihydrotestosterone

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5
Q

What is testosterone converted to?

A

Dihydrotestosterone

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6
Q

What is the name for undescended testes?

A

Cryptorchidism

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7
Q

Where is testosterone produced?

A

Leydig cells

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8
Q

Where are the spermatogenic cells located?

A

Seminferous tubule

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9
Q

What route does sperm take?

A

Testes - epididymis - vas deferens - ejaculatory duct - urethra

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10
Q

Name 3 causes of male infertility?

A
Low sperm count
Obstructive - congential, cf
Non obstructive - klinefelters, chemotherapy
Endocrine
Erectile difficulties
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11
Q

What is the indiction for intra-uterine insemination?

A

Low sperm count

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12
Q

What is the indication for surgical sperm aspiration?

A

Azoospermia

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13
Q

What is the indication for intracytoplasmic sperm injection?

A

Very low sperm count

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14
Q

What are the indications for donor sperm insemination?

A

Azoospermia, low sperm count, genetic conditions

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15
Q

What is the target for the HIV virus?

A

CD4+ receptors

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16
Q

Why does HIV cause susceptibility to infection?

A

Causes a reduction in proliferation and circulation of CD4 cells and a reduction in CD8 T cell activation

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17
Q

What is the normal range for CD4 cells?

A

500-1600cells/mm cubed

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18
Q

At what CD4 count is the risk of opportunistic infections highest?

A

Less than 200cm

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19
Q

When is a HIV primary infection likely to present and what are the symptoms?

A

2-4 weeks after infection

Fever, rash, myalgia, pharyngitis, headache

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20
Q

Name the 4 likely opportunistic infections in HIV?

And at what CD4 counts do they present?

A

Pneumocystis pneumonia - less than 200
TB
Cerebral toxoplasmosis - less than 150
Cytomegalovirus - less than 50

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21
Q

What organism causes pneumocystis pneumonia?

A

Pneumocystis jiroveci

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22
Q

What virus causes kaposi’s sarcoma?

A

Human herpes virus 8

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23
Q

What is the risk a baby of HIV infected mother will also become infected?

A

1 in 4

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24
Q

What is the most likely group to present with a late stage HIV infection?

A

Heterosexual men

25
What is thelarche?
Breast development
26
What is adrenarche?
Hair growth and pubic areas
27
Where is GnRH released from?
Hypothalamus
28
Where does GnRH act on and what does it cause the release of?
Anterior pituitary | LH and FSH
29
What triggers ovulation?
LH surge
30
At roughly what day in the cycle does ovulation occur?
Day 14
31
What hormone rises after ovulation?
Progesterone
32
What does the follicle become after ovulation and what hormone does it release?
Corpus luteum | Progesterone
33
If fertilisation occurs what does the developing fetus help to maintain?
Corpus luteum
34
What signals the end of the follicular phase?
Ovulation
35
What are the 2 stages of the menstrual cycle?
Follicular | Luteal
36
For women on anti-epileptics which contraceptives are UKMEC 1,2 and 3?
UKMEC 3 - COCP, POP UKMEC 2 - Implant UKMEC 1 - Depo, IUD, IUS
37
For women on lamotrigine which contraceptives are UKMEC 1,2 and 3?
UKMEC 3 - COCP | UKMEC 1 - POP, implant, Depo, IUS, IUS
38
What is metorrhagia?
Regular intermenstrual bleeding
39
What is polymenorrhoea?
Menses occurring at a less than 21 day interval
40
What is polymenorrhagia?
Increased bleeding and frequent cycle
41
What is menometorrhagia?
Prolonged menses and intermenstrual bleeding
42
What is oligomenorrhoea?
Menses at intervals greater than 35 days
43
What are the two types of dysfunctional uterine bleeding?
Anovulatory - extremes of reproductive age | Ovulatory
44
How long after UPSI does levonelle work?
72 hours
45
How long after UPSI does ellaOne work?
120 hours
46
What follow up should be given after emergency contraception?
Pregnancy test at 3 weeks
47
How long after UPSI can the copper IUD be used?
120 hours
48
When can medical TOP be performed?
Early - up to 9 weeks Late - 9-12 weeks Mid trimester - 12-24 weeks
49
When can vacuum aspiration be performed?
6-13 weeks
50
When can dilatation and evacuation be performed?
13-24 weeks - not available in scotland
51
What two drugs are given in a medical TOP?
Oral mifepristone | Vaginal or oral prostaglandin - 24-48 hours later
52
When can the second part of TOP be completed at home?
Before 9 weeks
53
Which serotypes of chlamydia are associated with lymphogranuloma venereum infection in MSM?
L1, L2, L3
54
What serotypes of chlamydia are most commonly associated with genital tract infection?
D-K
55
What is the starting rules for COCP?
Up to and including day 5 - no precautions | After day 5 - extra precautions
56
What are the starting rules for COCP in a non breastfeeding postpartum woman?
Up to day 21 - no precautions | After day 21- precautions
57
What are the starting rules for POP?
Up to and including day 5 - no precautions | After day 5 - precautions for 48 hours
58
When is COCP UKMEC 1 in breastfeeding women?
Only after 6 months
59
When is COCP UMKEC 1 in non breastfeeding postpartum women?
After 21 days