Reproductive Flashcards
When you think of cyclical pain what do you think of?
Endometriosis
3 D’s of endometriosis
Dysmenorrhea
Dyschezia
Dyspareunia
What does endometriosis often cause in women?
Infertility
Uterine characteristics in endometriosis
Fixed retroverted uterus with decreased mobility
+/- nodules in the rectovaginal septum
Test of choice and definitive diagnostic for endometriosis
TOC = TV U/S = Ground Glass Appearance
Def = Biopsy during laparoscopy
+”powder burn” and chocolate cysts with ovarian cysts+
Management of endometriosis
NSAIDS
COCs
Progestin
Danazol
GnRH agonists = leuprolide
If you want to treat endometriosis and save fertility potential what would you do?
Laporoscopy with ablation
What 3 types of fibriods arise from the myometrium
Submucosal
Intramural
Subserosal
What are the uterine findings commonly in fibriods
Firm Nontender irregular shaped.
What hormone controls uterine fibroids
Estrogen
3 sxs that can occur in uterine fibroid ; other wise ASX
Pelvic pressure / pain
Menorrhagia
Constipation
What imaging do you use to evaluate submucosa or intramural lesions?
Infusion sonohysterogram
What is the surgical management of fibriods that preserves fertility
Myomectomy
Def = hysterectomy
When thinking risk for endometrial cancer think
Increased estrogen exposure
MC type of endometrial cancer
Adenocarcinoma
MC GYN malignancy
How does ovulation effect endometrial cancer?
If you chronically dont ovulate [PCOS] you are more at risk
Suspect endometrial cancer if a women presents how?
Postmenopausal bleeding
During pelvic U/S endometrial stripe greater than what equals time for more imaging?
4mm ; get an endometrial biopsy
What is the med management of endometrial hyperplasia and when would you use it?
Progestin and only if patient still desires to be pregnant and there is no atypia present—> otherwise hysterectomy
Describe the 3 types of ovarian cysts
Follicular
Corpus luteum cyst
Neoplastic = #1 Teratoma ; Endometrioma ; Cystadenoma
What will ruptured ovarian cyst likely have (4)
Distention
Unilateral POOP
Fever
Guarding
What is the ovarian tumor marker
CA125
Follicular ovarian cyst U/S findings:
Unilocular thin walled anechoic
Corpus luteum cyst pelvic U/S findings
Diffuse thick walled with peripheral blood flow
What are the types of physiologic ovarian cysts
Follicular and corpus luteum
What size ovarian cyst usually requires surgery
Greater 5 cm
What 2 ligaments are involved in ovarian torsion
Infundibulopelvic and ovarian ligaments
What is the definitive diagnostic for ovarian torsion and what does it show
Laporoscopy
= enlarged ovary
Absent blood flow
Peripherally displaced follicles
What is the sign associated with Doppler flow U/S for ovarian torsion
Whirlpool sign = twisting of the vascular pedicle of the enlarged ovary
Remember that PCOS has increased what?
Insulin resistance with hyperinsuinemia
Lab findings in PCOS
Incr LH / FSH
Incr estrogen / progesterone
Incr total testosterone
Pelvic U/S findings in PCOS
Enlarged ovary multiple cysts
String of pearls
Can PCOS benefit from progestin only therapy
Yes — because PCOS lacks the ability to ovulate which requires progestin ; progestin is often low
What is the most common ovarian cancer ; common in what age
Epithelial Cell common in age over 50
What sxs do you think of with ovarian cancer and what risk factors
Abdominal Distention
Bloating
Early satiety
Weight loss
Virchows node and sister Mary and Joseph node can be present in what pelvic cancer
Ovarian cancer
Size greater than what is concerning for ovarian malignancy
10cm
What cervical cancer precursor is the most common etiology
HPV 16 and 18
What is a common findings in cervical dysplasia / cancer
Post coital bleeding
Does a woman with total hysterectomy need HPV or Pap testing
NO!
HPV screening is age what?
21-65
When can you consider HrHPV[preferred] or co testing every five years
WHAT ELSE?
Age 25 +
Pap test every 3 years ; starting at 21 +
What is the acetic acid stain for HSIL
Off white dull color
Coarse vascular pattern
When should a women be referred to colposcopy
Over 25 with LSIL or ASC-H
Over 29 with ASCU-US and +HPV
Age 21-24 with ASC-US or LSIL
And
Over 29 with HPV + and NILM
Repeat Pap in 1 year
Age over 29 ASCU-US and negative HPV
Repeat Pap in 3 years
What level of tissue change requires long term follow up 25 years +
CIN 2 and CIN 3
CIN2 but desires child bearing treatment
Excisional LEEP
4 signs of PID
Previous positive NAAT [G/C]
Fever
Muco discharge
ABD Pain /‘/ Postcoital bleeding
Dont forget to look for what in PID with pelvic U/S
Tubo-ovarian abscess
Out patient management of PID
Ceftriaxone + Doxy + Metronidazole
PID + Vibreonous string + Violin string adhesions = What syndrome?
Fitz Hugh Curtis
Dont forget what in BV
Usuallllllyyyyyy white copious discharge with odor due to increase in amines [FISHY]
3 of 4 criteria for BV include :
Thin white/gray discharge
Clue cells
pH of vaginal fluid greater than 4.5
Fish after whiff test 10% POTASSIUM HYDROXIDE
FIRST CHOICE for BV management
Metro by mouth BID x 7 days
2 important risk factors for yeast infection
Diabetes
Recent antibiotic use
Wet mount for yeast infection shows what
Psuedohyphe or spores
What would make a yeast infection complicated? (5)
Not infected by C. Albicans
Pregnant
Immune comp = Diabetes
Greater than 3 episodes per year
Severe sxs
How can you treat complicated yeast infection
Oral FLUCONAZOLE every 72 hours in 3-4 doses
Topical azole 7-14 days
Topical clotrimazole or Miconazole for 7 days if pregnant
Describe PE for Trichomonaisis
Frothy yellow-green discharge
Malodorous
Strawberry punctuate hemm cervix
Talk about TRICH treatment
Metro PO is first line ; 7 days
Tinadzole = 2nd
MUST TREAT PARTNER
Will amines be positive in TRICH?
Yes, bitch!
PALM COIEN for AUB
Polyp
ADENOMYOSIS
LEIOMYOMA
Malignancy
Coagulopathy
Ovulatory dysfunction
Endometrial
Iatrogenic
NOT CLASSED
Postcoital bleeding suggests what?
Cervical pathology
First line imaging for AUB
Pelvic U/S
What is hormonal vs non hormonal way to treat acute AUB ?
Hormonal = IV estrogen
Non hormonal = TXA ;; intrauterine Tamponade
3 thins common if no menarche before 15 with secondary sex characteristics
Outflow obstruction
Mullerian agenesis
Androgen sensitivity
3 etiologies of no menarche by 13 with no sex characteristics
Turner syndrome 45 XO
Illness, anorexia
Athletes
Dont forget what if your patient presents with amenorrhea
Check for pregnancy
What is ASHERMAN s syndrome
Intrauterine adhesions with fibrous tissue bands by trauma to the basal layer or INFECTION
What two heart complications are assoc with Turner’s syndrome
Coarctation of the aorta
And
Bicuspid aortic valves
Describe Turner’s syndrome 45XO
Low set ears
Wide set nipples
Web Neck
Minimal breast buds
Amenorrhea with which signs would make me concerned for pregnancy
Chadwicks and Hegars
What are the results of progesterone challenge in PCOS
Administer progesterone and get a withdrawal bleed, suggesting low levels of progestin
If there is no withdrawal bleed after progesterone challenge what can you do
Estrogen + progestin challenge
After estrogen progestin challenge if there is a withdrawal bleed what do you suspect
Primary ovarian failure
HYPOTHALMIC amenorrhea
After estrogen + progestin test is there is a withdrawal bleed what do you suspect
Primary ovarian failure
HYPOTHALMIC amenorrhea
If there is no withdrawal bleed after estrogen + progestin testing then what do you suspect?
ASHERMAN syndrome
Cervical stenosis
Lactational mastitis is most often due to what microbe?
Staph A.
Periductal non lactational mastitis can occur if patient has what 2 risk factors
Tobacco use
Squamous Metaplasia
Imaging studies for mastitis are only indicated when?
If patient is not lactating
What are the PO ABX of choice for mastitis
Dicloxacilin and cephalexin
MRSA txm think:
Bactrim
Unilateral fluctuant tender breast mass with fever think ;
Breast Abscess
U/S results of breast abscess are often
Ill defined borders with septations
Age most at risk for fibroadenoma
15-35
Firm round rubbery discrete non tender mobile breast mass is a ;
Fibroadenoma
What size fibroadenoma usually gets excised
Greater than 5 cm