Reproduction - QUIZ Flashcards

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1
Q

What is the role of LH and FSH in the process of spermatogenesis?

A

FSH: acts directly on the Sertoli cells to stimulate germ cell number
LH: acts on leydig cells to stimulate production of Testosterone

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2
Q

What is the role of LH and FSH in the process of oogenesis?

A

FSH: stimulates the growth of ovarian follicles in the ovary.
LH: helps control the menstrual cycle, surge triggers the release of an egg from the ovary.
Stimulate release of estrogen/ progesterone

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3
Q

What is the role of testosterone in the process of spermatogenesis and in the development of male sex characteristics?

A
  • Stimulates spermatogenesis
  • Stimulates development of male genitalia in fetus
  • Stimulates changes in development of adult male during puberty
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4
Q

What are the roles of estrogen and progesterone in the menstrual cycle/ oogenesis, in the development of female sex characteristics?

A
  • Progesterone causes thickening / repair of uterus lining / endometrium
  • Estrogen (high lvls) stimulates LH secretion (ovulation)
  • Cause development of female genitalia in the fetus & secondary sex characteristics
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5
Q

Know the roles of estrogen and progesterone during pregnancy and parturition (birth).

A
  • Progesterone maintains uterus lining during pregnancy, develops breast tissue, stops contractions
  • Estrogen triggers formation of fetal organs, regulates other hormones
  • Less p & more e leads to labor/contractions
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6
Q

Compare and contrast the processes of spermatogenesis and oogenesis.

A

BOTH:
- result in haploid gametes
- involve two divisions of meiosis
- stimulated by hormones
- involve differentiation
O: in ovaries S: in testes
O: starts during fetal development
S: Starts during puberty
O: one cell S: four sperm (meiosis)

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7
Q

Outline the genetic and hormonal control of the development of male and female sexual characteristics (prenatal).

A

Male:
- XY chromosomes (Y develops testes)
- Testes secrete testosterone (stimulates spermatogenesis)
/ sexual characteristics)
Female:
- XX chromosomes (can have both dominant / recessive alleles - hemophilia)
- Estrogen & progesterone cause development of genitals / secondary sex characteristics

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8
Q

Identify the hormones involved in the menstrual cycle and know the origin of each.

A
  • FSH and LH produced by pituitary gland
  • Estrogen / progesterone produced by ovaries
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9
Q

Explain the process of spermatogenesis.

A
  • Occurs in seminiferous tubule
  • Two divisions of meiosis:
    • Primary spermatocyte carries out first division
    • Secondary carries out second division
  • Meiosis produces haploid cells which differentiate into sperm cells
  • Sertoli cells help sperm to differentiate
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10
Q

Explain the process of oogenesis.

A
  • Oogenesis is the production of female gametes in the ovaries
  • Primary oocytes begin meiosis, arrested in prophase I to form follicles (until menstrual cycle)
  • Hormones (FSH / LH) trigger continued division of some primary oocytes
  • One cell forms secondary oocyte, while other cell forms a polar body (cytoplasm divided unequally)
  • 2nd oocyte begins the second meiotic division, arrested in metaphase II
  • Secondary oocyte released from the ovary (ovulation) & enters fallopian tube
  • If oocyte is fertilized chemical changes trigger completion of meiosis II (& formation of another polar body)
  • Once meiosis II is complete the mature egg (ovum) fuses nuclei with sperm nucleus (zygote)
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11
Q

What are the roles and concentrations of oxytocin, estriol (a type of estrogen), and prostaglandins in the positive feedback mechanisms of birth?

A
  • Estriol rises when stretch receptors detect child is too big
  • Estriol causes less progesterone / uterus to be more sensitive to oxytocin
  • Oxytocin causes uterine contractions
  • Less progesterone = more oxytocin
  • More contractions = more oxytocin (positive feedback)
  • Fetus responds w prostaglandins which cause more contractions
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12
Q

What are roles (and concentrations) of progesterone, prolactin, and oxytocin in the processes of breast development, milk production, and lactation?

A

Progesterone: increases number of mammary glands
Prolactin: milk production / development of mammary glands
Oxytocin: causes muscles around the mammary glands to contract

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13
Q

Where does fertilization take place?

A

In the fallopian tubes (oviduct).

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14
Q

Explain the process of fertilization (including the acrosome reaction), and including the mechanisms that prevent polyspermy (the cortical reaction).

A
  • Sperm enters fallopian tube & attaches to receptors in egg
  • Acrosome reaction; release of hydrolytic enzymes from acrosome (softens jelly coating)
  • Penetration of jelly coating, membranes of sperm and egg fuse
  • Cortical reaction; granules released to destroy binding sites outside of egg (prevents polyspermy)
  • Nucleus of 2nd oocyte completes meiosis II
  • Fusion of neucei, diploid zygote forms
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15
Q

What occurs after fertilization?

A
  • Cells inside undergo rapid mitotic divisions to form a blastocyst that implants in the uterine lining
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16
Q

What is the function and origin of the hormone hCG?

A

Function: promotes maintenance of the corpus luteum within the ovary / prevents degeneration
Origin: secreted by blastocyst in uterine lining

17
Q

Outline the structure and function of the placenta.

A

Structure: disc-shaped, connected via umbilical cord, umbilical arteries have thicker walls/wider lumen than veins
Function: Material exchange(oxygen, glucose, antibodies) / secretion of progesterone and estrogen

18
Q

Explain the process of IVF.

A
  • Drugs are used to down-regulate the menstrual cycle
  • FSH / HCG injected to stimulate development and maturation of follicles
  • Eggs are extracted / semen sample is collected
  • ICSI; sperm is directly injected into egg
  • Semen is mixed with eggs in a dish to allow fertilization (incubated at 37 degrees C)
  • Healthiest embryo is paced in uterus
  • Pregnancy test taken to see if procedure was successful
  • Used if parent is infertile (low sperm count, cannot get pregnant, etc.)