QUIZ - Hormones and Homeostasis Flashcards
Compare and contrast steroid and peptide hormones.
Steroid
- Non - Polar
- Bind to receptor proteins in the cytoplasm; forms a receptor-hormone complex
- Changes gene expression directly
- Slow onset but longer duration
Peptide
- Polar
- Bind to receptors in the plasma membrane of the target cell
- Activates a signal via second messenger systems
- Fast changes in protein activity
What is the role of the hypothalamus in hormonal secretion?
Controls hormonal secretions by the anterior and posterior pituitary
List examples of ANTERIOR pituitary hormones.
TSH, FSH, LH, Prolactin, and Growth hormone.
Target cells and function of TSH.
- Thyroid-stimulating hormone
- Targets cells of the thyroid to make and secrete thyroxine
Target cells and function of FSH.
- Follice-stimulating hormone
- Targets gonads in males and females
M : meiosis of spermocytes
F : maturation of oocyte
Target Cells and Function of LH.
- Luteinizing hormone
- Targets gonads in M/F
M : causes leydig cells to make testosterone
F : causes ovulation of oocyte
Target cells and function of Prolactin.
- Targets cells of the mammary glands causing them to grow / produce milk
Direct and indirect targets and effects/ actions of Growth hormone.
Direct : adipose tissue (reduces it)
Indirect : Muscles/bones
- Activates IGF (insulin growth factor) in liver which increases bone growth / muscle mass
Target cells and function of ADH.
- Targets cells of the kidney, increasing the amount of water that is reabsorbed into the blood
Target cells and function of Oxytocin.
- Produced in neurosecretory cells in hypothalamus but stored in/ secreted from posterior pituitary
- Targets cells of the uterine muscles / mammary glands, causing contractions (for birth) / milk secretion
Examples of posterior pituitary hormones.
ADH and Oxytocin
Explain the roles of the hypothalamus and thyroid gland in thermoregulation.
- Body temp is regulated by thyroxin (elevates metabolic rate = heat)
- Thermoreceptors in skin send signal to hypothalamus
Too cold - Hypothalamus sends TSH to anterior pituitary to release TRH -> thyroxin
Too hot - Hypothalamus inhibits production of thyroxin
- Lowers body temp
- Negative feedback
Explain the role of thyroxin and the causes and consequences of thyroxin deficiency.
- Thyroxin increases basal metabolic rate (production of heat – helps to control body temperature)
- By stimulating carb and lipid metabolism via oxidation of glucose / fatty acids
Cause: deficiency of iodine
Consequence: Enlarged thyroid (goiter)
Explain the role of melatonin in circadian rhythms.
- Circadian rhythms = body’s physiological response to the 24 hour day-night cycle
- Melatonin regulates circadian rhythms
- Photoreceptors (eyes) send signals to the hypothalamus
- Melatonin secreted by the pineal gland (brain)
- Melatonin release is inhibited by light (lvls high at night)
- High levels of melatonin promote sleep
Explain the causes and treatments of jet-lag.
Cause: The body’s inability to rapidly adjust to a new time zone due to extended air travel
Consequence: Taking melatonin during sleeping time of the new time zone