Repro/Obgyn Flashcards
Chandelier sign
pain on manipulation of the cervix and uterus during a pelvic examination in a patient with pelvic inflammatory disease.
PID complication
Salpingitis, endometritis, hydrosalpinx, tubo-ovarian abscess, Fitz-Hugh–Curtis syndrome
Fitz-Hugh–Curtis syndrome
infection of the liver capsule and “violin string” adhesions of peritoneum to liver
Thin white vaginal discharge, vaginal pH > 4.5, fishy odor on 10% potassium hydroxide “whiff” test, and clue cells on saline mount microscopy
Bacterial vaginosis via Gardnerella vaginalis; rx metronidazole or clindamycin.
Foul-smelling, greenish discharge; itching and burning; “strawberry cervix”; pH>4.5 ;dx/rx?
Trichomonas vaginalis, mobile protozoan with multiple flagella on microscopy; rx Metronidazole for patient and partner (prophylaxis)
Thick vaginal discharge, vaginal pruritus, dysuria, vaginal pH 4–5, dx/rx?
Vaginal candidiasis, budding hyphae or spores on 10% KOH; rx topical azole
Painful penile, vulvar, or cervical vesicles and ulcers; can cause systemic symptoms such as fever, headache, myalgia
Genital herpes (HSV2); rx Valacyclovir
Polyarthalgia, Tenosynovitis,, Vesiculopustular skin lesions, sexually active?
Disseminated Gonococcal infection
Urethritis, cervicitis, PID, prostatitis, epididymitis, arthritis, creamy purulent discharge
Neisseria gonorrhoeae; rx Ceftriaxone
Urethritis, cervicitis, conjunctivitis, reactive arthritis, PID
Chlamydia trachomatis (D-K)
Painful genital ulcer, inguinal adenopathy
Haemophilus ducreyi
Infection of lymphatics; painless genital ulcers, painful lymphadenopathy (i.e., buboes)
C. trachomatis (L1–L3)
Smooth pink teardrop-like lesions on vulva; dx/rx?
Condyloma acuminata (genital warts) HPV 6/11; rx trichloroacetic acid or podophyllin
Early decelerations, which begin and end at approximately the same time as the maternal contraction.
Vagal stimulation due to Fetal head compression
Severe late decelerations, and usually with absent variability
Myocardial depression is associated with severe acidosis and perinatal morbidity and mortality.
Mild late decelerations
CNS reflex response to fetal hypoxia, from uteroplacental insufficiency, a sign of placental abruption or hypotension.
Fetal alcohol sx features?
growth retardation (weight or height ≤ 10th percentile), facial dysmorphia (smooth philtrum, thin vermilion border, short palpebral fissures, hypoplastic midface, and microcephaly), CNS (structural or functional abnormalities, MR)
effects of beta-HCG on thyroid?
beta-HCG is a weak TSH-R stimulator, leading to increased T3/T4, increased TBG (even higher total T4), decreased TSH, subclinical hyperthyroidism
1st trimester screen w/ low maternal serum α-fetoprotein, low estriol, low β-HCG, low or normal inhibin A
Trisomy 18, Edward’s syndrome
1st trimester screen w/ low β-hCG, low PAPP-A, and nuchal translucency.
Patau syndrome Trisomy 13
1st trimester screen w/ nuchal translcency, hypoplastic nasal bone, low serum PAPP-A, increased free β-hCG
Down syndrome (trisomy 21), 1:700
2nd trimester screen w/ low α-fetoprotein and estriol, high β-hCG and inhibin A.
Down syndrome (trisomy 21), 1:700
1st trimester elevated maternal AFP?
Neural tube defect (anencephaly, spina bifida), GI defect (gastroschesis, omphalocele), multiple gestation
Child born w flat facial profile, prominent epicanthal folds, upslanting palpebral fissure, clinodactyly, simian crease, and congenital heart disease. 15–18 weeks of gestation triple marker screen shows?
Down’s sx 3markers: decreased alpha-fetoprotein and estradiol, increase beta-hcg
Child born w rocker-bottom feet, low-set ears, micrognathia, prominent occiput, clenched hands, and congenital heart disease.. 15–18 weeks of gestation triple marker screen shows?
Trisomy 18, Edward’s syndrome; decreased alpha-fetoprotein, estradiol, and beta-hcg
Irregular menses, infertility, LH:FSH ratio > 3, increased dehydroepiandrosterone; dx?
PCOS; b/c of elevated androgens and may also present with acne, hirsutism, and weight gain
Pt w/ hirsutism, menstrual abnormalities, obesity, acanthosis nigricans, and precocious puberty; increased risk for?
PCOS a/w breast and endometrial cancer secondary to unopposed estrogen; increased risk of infertility, metabolic syndrome, DMT2
Primary amenorrhea without secondary sexual characteristics, anosmia; dx?
Kallmann’s sx GnRH synthesis disorder w/ olfactory bulb agenesis