Cardio Flashcards
Continuous machinery murmur at the left upper sternal border
PDA: small PDA would be asymptomatic, whereas a large PDA would present in infancy with signs of heart failure, including failure to thrive, poor feeding, and respiratory distress.
Harsh holosystolic murmur at the left lower sternal border, with diastolic murmur at apex
ventricular septal defect (VSD). Neonates with isolated small VSDs are usually asymptomatic, whereas those with large VSDs present with signs of heart failure by 3–4 weeks of age
Widely split, fixed S2 and systolic ejection murmur at the left upper sternal border
atrial septal defect (ASD). Small ASDs do not cause symptoms in infancy and childhood. Those with large ASDs may develop heart failure, or present later in life with dyspnea, fatigue, and atrial arrhythmias.
Loud S2 (pulm HTN), systolic ejection murmur, holosystolic murmur at left upper sternal border; dx, a/w?
Complete arterioventricular septal defect, most common cardio defect in Downs (2nd VSD, 3rd ASD); may lead to pulm HTN
Cardiac sign in infant with the high-arched palate, webbed neck, widely spaced nipples, and edematous hands and feet
Turner’s syndrome: Bicuspid aortic valve and coarctation of the aorta: delayed femoral pulses suggest coarctation, a/w a systolic murmur loudest below the left scapula.
5 days post MI, sudden loss of HR, BP, and consciousness, while the ECG show a sinus rhythm.
Free wall rupture (5-10days post MI), may prevent w β- blockers, ACEis, avoid anti-inflammatory agents such as ibuprofen and indomethacin.
Patient rx for HTN now displays symptoms of angina, tachycardia, rash, and joint pains
Hydralazine: Lupus like sx
SE ACEi’s
dry cough (10–20% of people), hyperkalemia (blocks aldosterone secretion), angioedema, renal failure
SE β-Blockers
depression and erectile dysfunction, hypoglycemia via adrenergic blockade, hyperkalemia, pulmonary reactivity, bradycardia
SE: Calcium channel blockers such as verapamil
act as reverse chronotropes: bradycardia and even atrioventricular block; gingival hyperplasia and constipation
pt p/w acute chest pain(MI), time to therapy <12 H and STE > 2–3 mm in the chest leads and 1 mm in the limb leads.
Classic acute MI, and he has fulfilled all indications for fibrinolytic therapy: give TPA
advance cardiac life support bradycardia algorithm mnemonic: symptomatic brady (HR<60)
“All Trained Dogs Eat Iams”: Atropine (.5mg up to 3mg), Transcutaneous pacing, Dopamine, Epinephrine, and Isoproterenol, given in that order.
pt p/w vague abdominal sx, neurologic (headache, delirium), visual (altered color perception, scotomata), and cardiac arrhythmias (hyperkalemia, especially w K sparing diuretics)
Digoxin Toxicity; give Antidigoxigenin antibody Fab fragments; also renally secreted
Diastolic heart failure (dyspnea and increased venous pressure) in the setting of a normal ejection fraction and normal valvular function.
Diastolic failure is due to the inability of the ventricle to relax and properly fill during diastole. This results in a normal or decreased end-diastolic volume.
Pt p/w heart failure, arrhythmias, or even sudden death, Ejection Fr
Left ventricular dilation and systolic dysfunction: Dilated (LV) results in decreased contraction -> decreased LV ejection fraction
physical examination findings suggestive of aortic insufficiency
Diastolic murmur, Corrigan’s pulse (water-hammer pulse), de Musset’s sign (head bobbing), Traube’s sign (pistol-shot sound over the femoral artery), Duroziez’s sign (to-and-fro murmur over the femoral artery), Quincke’s pulse (capillary pulsation in the nail beds), or Hill’s sign (popliteal artery pressure greatly increased over brachial pressure).
Vegetative growth on a native mitral valve
Mitral valve prolapse, particularly as a complication of rheumatic heart disease, is a risk factor for native valve infective endocarditis.
Pt w/ holosystolic murmur at apex radiates to axilla; dx/sx features?
Mitral regurge; dry cough and exertional dyspnea (LV dysfnc, pulmonary edema HTN), aFib (LA dilatation)
Pt p/w fever, fatigue, malaise, Janeway lesions, and immunologic phenomena such as Osler nodes.
Infective endocarditis: IVDA -> Staphylococcus aureus acute endocarditis; prosthetic valve-> coagulase-negative staph; subacute-> Streptococcus viridans
Neonate p/w cyanosis and tachypnea. harsh holosystolic murmur at L lower sternal border; CXR: egg-shaped silhouette due to the absent main pulmonary artery stem and small heart base.
Dextraposed transposition of the great arteries (D-TGA); Prostaglandin E1 keep the PDA open. Balloon atrial septostomy. Arterial switch surg
Neonate p/w systolic ejection murmur at L upper sternal border, radiating to interscapular region. PE: weak, delayed femoral pulses relative v. UE, HTN in UE. CXR “reverse 3” sign, notched ribs
Coarctation of the aorta: acyanotic heart disease
Neurologic adverse effects of lidocaine
slurred speech and confusion. Other common adverse effects include tremor, personality and mood changes, and hallucinations
Lidocaine use in arrhythmias?
Used for treatment of ventricular arrhythmias (Vtach), should not use prophylactically b/c risk of asystole
Chest pain, fatigue, and dyspnea, +Beck’s triad: hypotension, distant heart sounds, distended neck veins
Cardiac Tamponade
Absolute contraindications to thrombolytics
hx cerebrovascular hemorrhage, ischemic stroke w/in 3 months, structural cerebral vascular lesion, brain tumor, active bleed/ coagulopathy, head/facial trauma w/in 3 months, aortic dissection
Extrarenal sx ADPCKD (polycystic kidney)
Cardiac - valvular dz (mitral prolapse, aortic regurge), cerebral aneurysm, hepatic cysts
Palpitations, SOB, Chest pain, hx COPD, EKG: varied PR interval, 3+ P wave morphologies
MAT: Multifocal Atrial Tachycardia, etiology: hypoxia (check O2 sats), CHF, electrolytes, sepsis
Symptomatic Mitral regurge 2/2 ischemic cardiomyopathy rx?
Loop Diuretics (decrease preload) + ACEi / beta-blocker (decrease afterload)
Indications for CABG?
significant L main coronary artery stenosis, >70% proximal stenosis LAD/L-circumflex, 3 vessel dz, symptomatic ischemic resistant to meds
EKG findings in Hypothermia
Osborn/J-waves: Upward deflection following R-wave (lead II)
EKG changes Hypokalemia
Diffuse broadening of T waves, prominent U waves; p/w hyporeflexia, flaccid paralysis, rhabdo, tetany, arrhytmias
EKG changes Hyperkalemia
Peaked T-waves, widened or sinusidal QRS, prolonged PR, ST depression
Hyperkalemia Rx
C BIG K: Calium gluconate, Bicarb/ Insulin & Glucose, Kayexalate
EKG changes in TCA o/d
Widened QRS (first), heart block, prolonged QT and PR
Best initial rx for TCA o/d
Bicarb: to increase pH, attenuates Na channel block
premature wide bizzarely shaped QRS complexes
premature ventricular contraction
Pre-excitation syndrome, (WPW) features
Short PR, aberrant conduction made worst by AV blocking agents: digoxin, CCB, b-blockers and may progress to SVT, VT
Irregular rhythm w absent P-waves
A-Fib
A-Fib w/ STEMI treatment
Beta-Blockers: reduce O2 demand, reduce rate [or w CCB, Digoxin], O2, Nitro, ASA; get cardiac enzymes; angioplasty, fibrinolysis, CABG
Narrow PR, Wide QRS, w/ slurred upstroke on EKG
WPW (wolf-parkinson-white) syndrome
WPW rx stable patient; may present w/ Afib w/ rapid ventricular response (risk of Vfib)
Procainamide (1st choice), 2nd try Amiodarone; definitive rx radiofrequency ablation
WPW rx unstable (hypoperfused, hypotense, tachy) patient
Synchronized cardioversion
Regular narrow complex tachycardia (not WPW) treatment
Adenosine
Rx: HTN + BPH
alpha-1 antagonist (terazosin)
Rx: HTN + Essential tremor/ hyperthyroid/ post-MI/ angina pectoris/ Glaucoma/ Headache/ Diastolic CHF
Beta-blockers (metoprolol)
Rx: HTN + CHF/ MI/ CKD proteinuria
ACE inhibitors (lisinopril)
Rx: HTN + Diastolic CHF/ recurrent SVT/ headache/ Raynaud/ Esophageal spasms/ Angina pectoris
CCB (verapamil - SVT, dihydropyridine - Raynaud)
Rx: HTN + CHF/ Edema/ Osteoporosis
1st line HTN: Thiazide diuretics
Rx: HTN emergency (a/w organ damage)
IV Labetalol, or IV Nitroprusside
Tachy, stable w/ pulse, regular rhythm (SVT) rx?
Vagal maneuvers, Atropine, Amiodarone if unsuccessful
Rx for pt w/ blowing systolic murmur @aorta, JVD, pulmonary congestion, pedal edema, liver congestion
Aortic regurge: backward failure sd: L CHF (pulmonary congestion) -> R CHF (JVD…) ->Rx ACEi (Captopril/ Spioinolactone)
Pt w/ ACS sx, what given hx indicates Echo vs. EKG for dx?
Previous MI, previous LBBB, on Digoxin, pacemaker
Shock? Decreased CO, Low PCWP, Increased SVR, Low Venous O2
Hypovolemic
Shock? Decreased CO, High PCWP, Increased SVR, Low Venous O2
Cardiogenic
Shock? Decreased CO, Low PCWP, Low SVR, Low Venous O2
Neurogenic
Shock? Increased CO, Low PCWP, Decreased SVR, Increased Venous O2
Septic