Repro Flashcards

1
Q

CI IUD

A

unexplained vaginal bleeding
PID/cervicitis
cervical/uterine CA, 2 atypical paps
hx heart valve or artificial joint replacement

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2
Q

oligomenorrhea

A

longer time between periods

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3
Q

polymenorhea

A

frequent < 21 D cycle

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4
Q

menorrhagia

A

lots of flow

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5
Q

metrorrhagia

A

bleeding between periods

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6
Q

menometrorrhagia

A

excessive + irregular bleeding

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7
Q

AUB tx

A

1) NSAID to decrease blood loss

heavy bleeding - estrogen IV, then DnC
anovulatory bleding - OCP, mirena

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8
Q

21 hydroxylase deficiency

A

congenital adrenal hyperplasia
ambiguous genitals
salt wasting

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9
Q

“pearl necklace sign”

A

PCOS

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10
Q

dx PID

A

lower abd/pelvic pain + 1 of the following:
uterine tenderness
adenexal tenderness
CMT

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11
Q

outpt tx PID

A

1) rocephin +/- doxy x 14 D

2) levofloxacin x 14D +/- flagyl

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12
Q

inpt tx PID

A

1) foxy-doxy x 14D

2) clindamycine + gentamicin

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13
Q

most are asx
long/heavy periods, pressure, pain
lumpy bumpy uterus

A

leiomyoma (fibroids)
estrogen/progesterone sensitive
increase in size w/ pregnancy and decrease in menopause
tx: NSAID, OCP

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14
Q

tx fibroids to stop bleeding vs decrease size myomas

A

danazol - stop bleeding

Leuprolide (GnRH) - decrease size

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15
Q

MCC endometrial CA

A

endometrioid
favorable prognosis
assoc w/ unopposed estrogen (tamoxifen use)

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16
Q

type of endometrial CA assoc w/ p53 mutation

A

serous

poor prognosis

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17
Q

HPV 16 vs 18 association w/ adeno vs squamous cervical CA

A
Sixteen = Squamous
AYE-teen = Adeno
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18
Q

RF cervical CA

A

STD/HIV
smoking
lots of babies
OCP

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19
Q

ssx cervical CA

A

metrorrhagia (bleeding between periods)
post-sex spotting
cervical ulceration

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20
Q

CIN 1 treatment

A

after 2 neg pap at 6 and 12 mon, continue w/ Q1yr

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21
Q

CIN I, II, III w/ negative margins tx

A

pap at 12 mon +/- cotest

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22
Q

CIN II, III w/ positive margins

A

pap at 6 mon, consider edocervical curettage

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23
Q

CIN II and III tx or persistent CIN I

A

ablation = cryotherapy or laser
excision = leep
hysterectomy if really bad

24
Q

RF vulvar CA

A

HPV 16, 18, 31
lichen sclerosus
diabetes/obesity/HTN/CAD

25
Q

what is VIN

A

vulvar interepithelial neoplasa

PRE-cancerous in PRE-menopausal F

26
Q

purritus, pain, ulceration of mass

A

vulvar ca
punch bx
tx: chemo, ablation, vulvectomy

27
Q

typically found in upper 1/3 vagina

sx: abnormal bleeding, d/c, or post-sex bleeding

A

vaginal CA

tx: excise

28
Q

types of pts and types of vaginal CA typical

A

postmenopause = squamous
young = adeno
DES exposure = clear cell

29
Q

BRCA 1 > BRCA 2
lynch syndrome
CA 125

A

ovary CA
1st step: TVUS
tx: TAHBSO w/ omenectomy + lymphadenectomy + chemo post-op

30
Q

tx precocious puberty

A

central - leuprolide

31
Q
MC of all benign breast conditions
exaggerated stromal tissue
30-50y/o
assoc w/ trauma and caffeine
cyclical, bilateral
A

fibrocystic changes of breast

32
Q

MC breast lesion in women < 30

do NOT change w/ cycle

A

fibroadenoma

cystosarcoma phyllodes = large fibroadenoma

33
Q

bx breast CA

A

FNA - initial bx

core needle - large sample to check receptor status

34
Q

tumor markers breast CA

A

CEA
CA 15-3
CA 27-29

35
Q

tx breast CA

A

hormone receptor+: tamoxifen
estrogen receptor-: chemo
HER2/neu: trastuzumab

36
Q

complications metastatic breast CA

A

Pleural effusion, edema of arm

37
Q

CI lumpectomy

A
large tumor or multiples
subareolar
fixated to chest wall
prior radiation
nipple involvement
38
Q

bHCG levels

A

peak at 100K at 10 weeks, decreases throughout 2nd trimester, levels of in 3rd
should double Q48H in early prego

39
Q

used to confirm pregnancy

A

US - gestational sac seen at 5 weeks

bHCG around 1000-1500

40
Q

physiologic changes in pregnancy

A

CO, tidal volume, respirations, blood volume, gastric emptying time - increase
blood pressure, HCT, sphincter tone - decrease

41
Q

“UNDERage at 18”

A

trisomy 18

AFP, estriol, b-hcg, inhibin A are ALL low

42
Q

“2 down, 2 up”

A

trisomy 21
AFP/estriol - down
b-hcg, inhibin A - up

43
Q

when to do amniocentesis

A

> 35 gest age + abnormal quad screen

44
Q

TORCHES causes

A
premature delivery
CNS abnormalities
anemia
jaundice
hepatosplenomegaly
growth retardation
45
Q

TORCHES pathogens

A
Toxoplasmosis
Other - parvovirus, varicella, listeria, TB, malaria
Rubella
Cmv
HSV/HIV
Syphilis
46
Q

latent vs active 1st stage labor

A

latent: onset till 3-4cm dilated
active: 4cm till 10

47
Q

fetal heart rate monitoring components

A

heart rate
variability
accelerations
decelerations

48
Q

fetal decelerations

A

early - normal (head compression from uterine conraction)
late - fetal hyoxemia, uteroplacental insufficeincy
variable - umbilical cord compression

49
Q

HELLP syndrome

A

variant of preeclampsia w/ poor prognosis

hemolysis, elevated LFT, low platelet

50
Q

triad preeclampsia is not just “HyPE”

A

Htn
Proteinuria
Edema

51
Q

wood’s screw vs mcroberts maneuvers

A

wood screw - rotation

mcroberts - leg elevation

52
Q

frank vs complete breech

A

complete knees are flexed, frank knees are extended

both have hips flexed

53
Q

immunity provided in colostrum

A

secretory IgA

54
Q

CI breast feeding

A

maternal HIV
active TB
drug abuse

55
Q

failure to lactate from low prolactin levels

A

Sheehan’s

56
Q

tx mastitis

A

dicloxacillin
keflex
augmentin
macrolide