Derm Flashcards
Anaphylactic and atopic derm hypersensitivity mechanism
IgE (Type 1)
Cytotosic hypersensitivity mechanism
IgM and IgG (Type 2)
Cell-mediated/delayed
sensitized T lymphocytes (Type 4)
TB skin tests, contact dermatitis
pityrosporum ovale
yeast
seborrheic derm
tx: selenicum sulfid, zince pyrithione, emollients
red plaquest + silvery scales on extensor surfaces
psoriasis - T cell mediated
Koebner’s pheominon
Auspitz +
Tx psoriasis
sopical steroids
methotrexate
retin A or D3
hives
Type 1 sensitivity
chronic > 6wk
tx: systemic antihistamines
targetoid lesions esp on mucous membranes
can be blisters and affect palms and soles
triggers: HSV, drugs, mycoplasm
erythemia multiforme
tx: antipururitics or tx as burn
Nikolsky +
SJS
pemphigus vulgaris
panniculitis (inflammation of SQ adipose tissue)
triggers: infxn, drugs (sulfs, OCP), chronic inflammatory dz (sarcoid, UC, Crohn’s)
PAINFUL red nodules on lower legs
erythema nodosum
can have false + VDRL
tx: spontaneously resolve w/o ulcers
dermatitis herpetiformis is associated w/?
celiace dz
tx: dapsone + gluten free
older
tese blisters
nikolsky -
idiopathic
bullous pemphigoid
tx: prednisone
40-60 y/o
flaccid blisters + erosions
Nikolsky +
assoc w/ ACEI, penicillamine, phenobarbital, PCN
pemphigus vullgaris
tx: high dose prednisone + immuno therapy
tx verrucae (HPV)
cryotherapy
podophyllin
tricholoacetic acid
imiquimod
cause impetigo
group A strep and staph